FUSED MULTICYCLIC COMPOUNDS AND THEIR USE AS PARP1 INHIBITORS

Title:

FUSED MULTICYCLIC COMPOUNDS AND THEIR USE AS PARP1 INHIBITORS

Document Type and Number:

WIPO Patent Application WO/2024/099364

Kind Code:

A3

Abstract:

Provided herein are certain fused multicyclic compounds with a multicyclic linker, such as a compound of Formula (I), as PARP1 inhibitors, pharmaceutical compositions comprising the compounds, and method of use of the compounds or pharmaceutical compositions in the treatment of diseases or disorders.

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Inventors:

LI MING (CN)
CHEN YAN (CN)
CHEN CHUN-YEN (CN)
GU XIANG-JU JUSTIN (CN)

Application Number:

PCT/CN2023/130493

Publication Date:

June 13, 2024

Filing Date:

November 08, 2023

Export Citation:

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Assignee:

LAEKNA THERAPEUTICS SHANGHAI CO LTD (CN)

International Classes:

A61P35/00; A61K31/407; A61K31/436; A61K31/4375; A61K31/498; A61K31/4985; C07D487/04; C07D519/00

Attorney, Agent or Firm:

AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)

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