Title:
GENETICALLY-MODIFIED POULTRY EGG
Document Type and Number:
WIPO Patent Application WO/2017/111144
Kind Code:
A1
Abstract:
Provided are a poultry knock-in egg and knock-out egg. The present invention pertains to a knock-out poultry egg in which at least one oviduct-specific gene has been knocked out, said gene being selected from the group consisting of ovalbumin, ovomucoid, ovomucin, ovotransferrin, ovoinhibitor, and lysozyme, and at least one egg allergen protein has been reduced or eliminated, said protein being selected from the group consisting of ovalbumin, ovomucoid, ovomucin, ovotransferrin, ovoinhibitor, and lysozyme.
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Inventors:
OISHI ISAO (JP)
YOSHII KYOKO (JP)
YOSHII KYOKO (JP)
Application Number:
PCT/JP2016/088590
Publication Date:
June 29, 2017
Filing Date:
December 22, 2016
Export Citation:
Assignee:
NAT INST ADVANCED IND SCIENCE & TECH (JP)
International Classes:
A01K67/027; C12N15/00; C12N15/09; C12P21/00
Domestic Patent References:
| WO2015199225A1 | 2015-12-30 |
Foreign References:
| JP2015514404A | 2015-05-21 | |||
| JP2011010598A | 2011-01-20 | |||
| KR20160073469A | 2016-06-27 |
Other References:
PARK, T. S. ET AL.: "Targeted gene knockout in chickens mediated by TALENs", PNAS, vol. 111, no. 35, 2014, pages 12716 - 12721, XP055248659
FAN, B. ET AL.: "Assembly and in vitro functional analysis of zinc finger nuclease specific to the 3' untranslated region of chicken ovalbumin gene", ANIMAL BIOTECHNOLOGY, vol. 22, October 2011 (2011-10-01), pages 211 - 222, XP055173589
HIROYUKI HORIUCHI: "Idenshi Kaihen-kei no Kaihatsu de Tamago Allergy Kokufuku ni Idomu Allergy Free no Tamago Kaihatsu ga Kano ka", THE NIWATORI-NO-KENKYU, SPECIAL EXTRA ISSUE, vol. 5, 2010, pages 5 - 7
TAKASHI YAMAMOTO ET AL.: "Genome Henshu o Riyo shita Baiyo Saibo ya Dobutsu ni Okeru Hyoteki Idenshi no Kaihen", JAPANESE JOURNAL OF CIRCULATION RESEARCH, vol. 36, no. 4, 2013, pages 123 - 128
ISAO OISHI ET AL.: "Gairai Idenshi o Antei Hatsugen suru Kumikae Niwatori Juritsu no Kokoromi", JAPANESE JOURNAL OF POULTRY SCIENCE, vol. 52, 2015, pages 7
PARK, T. S. ET AL.: "Germ Cell , Stem Cell , and Genomic Modification in Birds", J. STEM CELL RES. THER., vol. 4, no. 5, 2014, pages 1 - 6, XP055248662
REIKO TEJIMA: "Genome Henshu Dobu tsu Yurai Shokuhin no Anzensei Hyoka ni Kansuru Kenkyu , Kosei Rodosho Kagaku Kenkyuhi Hojokin (Shokuhin no Anzen Kakuho Suishin Kenkyu Jigyo) ' Shin Kaihatsu Biotechnology Oyo Shokuhin no Anzensei Kakuho Narabini Kokumin Juyo ni Kansuru Kenkyu", KYORYOKU KENKYU HOKOKUSHO, 2015, pages 29 - 34
FAN, B. ET AL.: "Assembly and in vitro functional analysis of zinc finger nuclease specific to the 3' untranslated region of chicken ovalbumin gene", ANIMAL BIOTECHNOLOGY, vol. 22, October 2011 (2011-10-01), pages 211 - 222, XP055173589
HIROYUKI HORIUCHI: "Idenshi Kaihen-kei no Kaihatsu de Tamago Allergy Kokufuku ni Idomu Allergy Free no Tamago Kaihatsu ga Kano ka", THE NIWATORI-NO-KENKYU, SPECIAL EXTRA ISSUE, vol. 5, 2010, pages 5 - 7
TAKASHI YAMAMOTO ET AL.: "Genome Henshu o Riyo shita Baiyo Saibo ya Dobutsu ni Okeru Hyoteki Idenshi no Kaihen", JAPANESE JOURNAL OF CIRCULATION RESEARCH, vol. 36, no. 4, 2013, pages 123 - 128
ISAO OISHI ET AL.: "Gairai Idenshi o Antei Hatsugen suru Kumikae Niwatori Juritsu no Kokoromi", JAPANESE JOURNAL OF POULTRY SCIENCE, vol. 52, 2015, pages 7
PARK, T. S. ET AL.: "Germ Cell , Stem Cell , and Genomic Modification in Birds", J. STEM CELL RES. THER., vol. 4, no. 5, 2014, pages 1 - 6, XP055248662
REIKO TEJIMA: "Genome Henshu Dobu tsu Yurai Shokuhin no Anzensei Hyoka ni Kansuru Kenkyu , Kosei Rodosho Kagaku Kenkyuhi Hojokin (Shokuhin no Anzen Kakuho Suishin Kenkyu Jigyo) ' Shin Kaihatsu Biotechnology Oyo Shokuhin no Anzensei Kakuho Narabini Kokumin Juyo ni Kansuru Kenkyu", KYORYOKU KENKYU HOKOKUSHO, 2015, pages 29 - 34
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