Title:
GRF2-BINDING PROTEINS AND APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO2002002629
Kind Code:
A3
Abstract:
Reagents and methods of use thereof regarding proteins and complexes of GRF2-interacting proteins (GRF2-IP) and proteins interaction with GRF2-IP, as well as polynucleotides encoding those proteins.
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Inventors:
MCBROOM LINDA (CA)
MORAN MICHAEL F (CA)
ORNATZSKY OLGA (CA)
MORAN MICHAEL F (CA)
ORNATZSKY OLGA (CA)
Application Number:
PCT/CA2001/000941
Publication Date:
September 06, 2002
Filing Date:
June 29, 2001
Export Citation:
Assignee:
MDS PROTEOMICS INC (CA)
MCBROOM LINDA (CA)
MORAN MICHAEL F (CA)
ORNATZSKY OLGA (CA)
MCBROOM LINDA (CA)
MORAN MICHAEL F (CA)
ORNATZSKY OLGA (CA)
International Classes:
C12N15/09; A61K45/00; A61P9/10; A61P17/06; A61P19/00; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P35/02; A61P43/00; C07K14/47; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/07; C12N5/071; C12N5/10; C12Q1/02; C12Q1/68; (IPC1-7): C12N15/12; C07K14/47; C12N5/10; G01N33/68
Other References:
FAM, NP ET AL.: "Cloning and Characterization of Ras-GRF2, a Novel Guanine Nucleotide Exchange Factor for Ras", MOL. CELL. BIOL., vol. 17, no. 3, March 1997 (1997-03-01), pages 1396 - 1406, XP002189923
KRAPIVINSKY, G ET AL.: "pICln Binds to a Mammalian Homolog of a yeast Protein Involved in Regulation of Cell Morphology", J. BIOL. CHEM., vol. 273, no. 18, 1 May 1998 (1998-05-01), pages 10811 - 10814, XP002189924
PU, WT ET AL.: "pICln Inhibits snRNP Biogenesis by Binding Core Spliceosomal Proteins", MOL. CELL. BIOL., vol. 19, no. 6, June 1999 (1999-06-01), pages 4113 - 4120, XP002189925
KRAPIVINSKY, G ET AL.: "pICln Binds to a Mammalian Homolog of a yeast Protein Involved in Regulation of Cell Morphology", J. BIOL. CHEM., vol. 273, no. 18, 1 May 1998 (1998-05-01), pages 10811 - 10814, XP002189924
PU, WT ET AL.: "pICln Inhibits snRNP Biogenesis by Binding Core Spliceosomal Proteins", MOL. CELL. BIOL., vol. 19, no. 6, June 1999 (1999-06-01), pages 4113 - 4120, XP002189925
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