Title:
IMMUNOGLOBULIN-BINDING PROTEIN, AND AFFINITY CARRIER USING SAME
Document Type and Number:
WIPO Patent Application WO/2020/040307
Kind Code:
A1
Abstract:
Provided is an affinity carrier having improved alkali resistance. This immunoglobulin-binding protein contains a mutant polypeptide chain. This affinity carrier includes a solid-phase carrier to which the immunoglobulin-binding protein is bound. The mutant polypeptide chain has an amino acid sequence having at least 85% identity to an amino acid sequence indicated by any of SEQ ID NO: 1-6 and 57-62 and having a predetermined mutation, and has immunoglobulin-binding activity.
Inventors:
HAGA TOMOAKI (JP)
ICHII TAKASHI (JP)
ONOGI SHUNSUKE (JP)
NAKAMURA SATOSHI (JP)
HONDA TOSHINARI (JP)
KAMIDE TOMOYUKI (JP)
ICHII TAKASHI (JP)
ONOGI SHUNSUKE (JP)
NAKAMURA SATOSHI (JP)
HONDA TOSHINARI (JP)
KAMIDE TOMOYUKI (JP)
Application Number:
PCT/JP2019/033138
Publication Date:
February 27, 2020
Filing Date:
August 23, 2019
Export Citation:
Assignee:
JSR CORP (JP)
JSR MICRO INC (US)
JSR MICRO N V (BE)
JSR MICRO INC (US)
JSR MICRO N V (BE)
International Classes:
C12N15/31; C07K1/22; C07K14/315; C07K16/00; C07K17/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/10; C12N15/63; C12P21/02; G01N33/53; G01N33/566
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Other References:
JOURNAL OF CHROMATOGRAPHY B, vol. 848, no. 1, 2007, pages 40 - 47
PRO. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
THOMPSON, J. D ET AL., NUCLEIC ACIDS RES., vol. 22, 1994, pages 4673 - 4680
PNAS, vol. 86, 1989, pages 8247 - 8251
GENE, vol. 77, 1989, pages 61 - 68
FREDERICK M. AUSBEL ET AL.: "Current Protocols In Molecular Biology", 2001, COLD SPRING HARBOR LABORATORY PRESS
J. MATER. CHEM, vol. 1, no. 3, 1991, pages 371 - 374
PRO. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
THOMPSON, J. D ET AL., NUCLEIC ACIDS RES., vol. 22, 1994, pages 4673 - 4680
PNAS, vol. 86, 1989, pages 8247 - 8251
GENE, vol. 77, 1989, pages 61 - 68
FREDERICK M. AUSBEL ET AL.: "Current Protocols In Molecular Biology", 2001, COLD SPRING HARBOR LABORATORY PRESS
J. MATER. CHEM, vol. 1, no. 3, 1991, pages 371 - 374
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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