Title:
MCI DIAGNOSTIC MARKER, MCI DIAGNOSTIC KIT, AND CORRESPONDING DETECTION METHOD
Document Type and Number:
WIPO Patent Application WO/2022/022060
Kind Code:
A1
Abstract:
Disclosed is a diagnostic marker for prodromal stage Mild Cognitive Impairment (MCI) of the Alzheimer's disease. The marker is plasma long-chain non-coding ribonucleic acid (lncRNA), comprising one or more of ENST00000549762, NR_024049, T324988 or ENST00000567919. Also disclosed are an application of the marker and a corresponding kit.
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Inventors:
WANG TAO (CN)
ZHANG WEI (CN)
XIAO SHIFU (CN)
ZHANG WEI (CN)
XIAO SHIFU (CN)
Application Number:
PCT/CN2021/098317
Publication Date:
February 03, 2022
Filing Date:
June 04, 2021
Export Citation:
Assignee:
SHANGHAI MENTAL HEALTH CENTER SHANGHAI PSYCHOLOGICAL COUNSELLING TRAINING CENTER (CN)
International Classes:
C12N15/113; C12Q1/68
Domestic Patent References:
| WO2020049135A1 | 2020-03-12 |
Foreign References:
| CN111690739A | 2020-09-22 | |||
| CN106978507A | 2017-07-25 | |||
| CN108866182A | 2018-11-23 | |||
| CN111373052A | 2020-07-03 | |||
| CN202010760263A | 2020-07-31 |
Other References:
SEREBROVSKA ZOYA O., SEREBROVSKA TETIANA V., KHOLIN VIKTOR A., TUMANOVSKA LESYA V., SHYSH ANGELA M., PASHEVIN DENIS A., GONCHAROV : "Intermittent Hypoxia-Hyperoxia Training Improves Cognitive Function and Decreases Circulating Biomarkers of Alzheimer’s Disease in Patients with Mild Cognitive Impairment: A Pilot Study", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL (MDPI), BASEL, CH, vol. 20, no. 21, 5405, 1 November 2019 (2019-11-01), Basel, CH , pages 5405 - 17, XP055893631, ISSN: 1661-6596, DOI: 10.3390/ijms20215405
See also references of EP 4190899A4
See also references of EP 4190899A4
Attorney, Agent or Firm:
SHANGHAI ZHI XIN PATENT AGENT LTD. (CN)
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