METHOD FOR THE PRODUCTION OF A STABLE INJECTABLE FORMULATION MADE OF DIFFICULT TO DISSOLVE ANTINEOPLASTIC ACTIVE SUBSTANCES

Title:

METHOD FOR THE PRODUCTION OF A STABLE INJECTABLE FORMULATION MADE OF DIFFICULT TO DISSOLVE ANTINEOPLASTIC ACTIVE SUBSTANCES

Document Type and Number:

WIPO Patent Application WO2004100994

Kind Code:

A3

Abstract:

The invention relates to a method for the production of a stable injectable formulation of antineoplastic active substances which are difficult to dissolve. A formulation containing the antineoplastic active substance and a solvent and/or a solvent system containing, optionally, a solubilisation agent is treated with a cation exchanger.

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Inventors:

EIDENHAMMER GERHARD (AT)
SCHNAIT HEINZ (AT)

Application Number:

PCT/EP2004/005268

Publication Date:

May 06, 2005

Filing Date:

May 17, 2004

Export Citation:

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Assignee:

EBEWE PHARMA GMBH NFG KG (AT)
EIDENHAMMER GERHARD (AT)
SCHNAIT HEINZ (AT)

International Classes:

A61K9/00; A61K31/337; A61K47/10; A61K47/44; (IPC1-7): A61K47/44; A61K47/10

Domestic Patent References:

WO2000023070A1	2000-04-27
WO1999033780A1	1999-07-08
WO1997012017A1	1997-04-03

Foreign References:

EP0645145A2

1995-03-29

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