Title:
METHODS OF PRODUCING AND CHARACTERIZING VIRUS VACCINE AND VIRUS VACCINE COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2018/161858
Kind Code:
A1
Abstract:
Provided are methods of isolating virus particles and producing virus vaccine composition comprising subject a biological sample to an anion exchange chromatography and a hydroxyapatite chromatography. Also provided are rabies virus vaccine compositions and methods of assessing suitability of a virus vaccine composition or releasing a commercial batch of virus vaccine composition for clinical use.
Inventors:
LIU DIANLIAN (CN)
AI WEN (CN)
SHEN MINGFENG (CN)
AI WEN (CN)
SHEN MINGFENG (CN)
Application Number:
PCT/CN2018/077905
Publication Date:
September 13, 2018
Filing Date:
March 02, 2018
Export Citation:
Assignee:
GUANGZHOU REALBENEFITSPOT PHARMACEUTICAL CO LTD (CN)
GUANGZHOU YINHEYANGGUANG BIOLOGICS CO LTD (CN)
GUANGZHOU YINHEYANGGUANG BIOLOGICS CO LTD (CN)
International Classes:
C12N7/02; A61K39/12; C07K1/18; C07K1/22; C07K14/005
Domestic Patent References:
| WO2010065520A1 | 2010-06-10 | |||
| WO2012061815A2 | 2012-05-10 | |||
| WO2011011390A1 | 2011-01-27 | |||
| WO2006136566A1 | 2006-12-28 | |||
| WO2005093049A1 | 2005-10-06 |
Foreign References:
| CN102171334B | 2015-05-27 | |||
| CN105378074A | 2016-03-02 | |||
| US20140004145A1 | 2014-01-02 | |||
| US20100260798A1 | 2010-10-14 | |||
| US20090247735A1 | 2009-10-01 | |||
| EP0171771A2 | 1986-02-19 |
Other References:
KANG, H ET AL., VIRUSES, vol. 7, no. 3, 2015
DIETZSCHOLD, B, CURRENT LABORATORY TECHNIQUES IN RABIES DIAGNOSIS, RESEARCH AND PREVENTION, vol. 2, 2015, pages 47 - 56
KUROSAWA ET AL., WORLD JOURNAL OF VACCINES, vol. 2, 2012, pages 155 - 160
GAGNON, P: "Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology", 2009, pages: 1 - 20
MICHEN, B.GRAULE, T., JOURNAL OF APPLIED MICROBIOLOGY, vol. 109, no. 2, 2010, pages 388 - 397
SOKOL, F ET AL., JOURNAL OF VIROLOGY, vol. 2, no. 8, 1968, pages 836 - 849
KUIPER, M ET AL., BIOTECHNOLOGY AND BIOENGINEERING, vol. 80, no. 4, 2002, pages 445 - 453
PATO, T. P. ET AL., VACCINE, vol. 32, no. 24, 2014, pages 2789 - 2793
"Pharmacopoeia of the People's Republic of China", vol. 3, 2015
DIETZSCHOLD, B, CURRENT LABORATORY TECHNIQUES IN RABIES DIAGNOSIS, RESEARCH AND PREVENTION, vol. 2, 2015, pages 47 - 56
KUROSAWA ET AL., WORLD JOURNAL OF VACCINES, vol. 2, 2012, pages 155 - 160
GAGNON, P: "Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology", 2009, pages: 1 - 20
MICHEN, B.GRAULE, T., JOURNAL OF APPLIED MICROBIOLOGY, vol. 109, no. 2, 2010, pages 388 - 397
SOKOL, F ET AL., JOURNAL OF VIROLOGY, vol. 2, no. 8, 1968, pages 836 - 849
KUIPER, M ET AL., BIOTECHNOLOGY AND BIOENGINEERING, vol. 80, no. 4, 2002, pages 445 - 453
PATO, T. P. ET AL., VACCINE, vol. 32, no. 24, 2014, pages 2789 - 2793
"Pharmacopoeia of the People's Republic of China", vol. 3, 2015
Attorney, Agent or Firm:
JIAQUAN IP LAW FIRM (CN)
Download PDF:
Previous Patent: ORDER INFORMATION DETERMINING METHOD AND APPARATUS
Next Patent: HYBRID BONDING CONTACT STRUCTURE OF THREE-DIMENSIONAL MEMORY DEVICE
Next Patent: HYBRID BONDING CONTACT STRUCTURE OF THREE-DIMENSIONAL MEMORY DEVICE