Title:
NOVEL TRICISTRONIC VECTORS AND USES THEREFOR
Document Type and Number:
WIPO Patent Application WO2004013276
Kind Code:
A9
Abstract:
A tricistronic vector (i.e., a vector capable of expressing three exogenous genes, which are not fused together, under the control of one promoter) effectively can encode an immunoglobulin-presenting polypeptide and two immunoglobulin (Ig) polypeptides. The encoded Ig-presenting polypeptide is able to associate with at least one of the Ig polypeptides via co-expressed associating agents. A vector according to the present invention particularly is suited for phage display technology, e.g., when the Ig-presenting polypeptide is a phage coat protein and the Ig polypeptides associate to form a Fab.
Inventors:
PRASSLER JOSEF (DE)
STARK YVONNE (DE)
STARK YVONNE (DE)
Application Number:
PCT/IB2003/003681
Publication Date:
April 01, 2004
Filing Date:
July 30, 2003
Export Citation:
Assignee:
MORPHOSYS IP GMBH (DE)
PRASSLER JOSEF (DE)
STARK YVONNE (DE)
PRASSLER JOSEF (DE)
STARK YVONNE (DE)
International Classes:
C07K16/00; C07K16/28; C12N15/10; C40B40/02; (IPC1-7): C12N/
Download PDF: