PHARMACEUTICAL ZEOLITE-BASED COMPOSITIONS CONTAINING ZINC AND ERYTHROMYCIN, TO BE USED IN THE TREATMENT OF ACNE

Title:

PHARMACEUTICAL ZEOLITE-BASED COMPOSITIONS CONTAINING ZINC AND ERYTHROMYCIN, TO BE USED IN THE TREATMENT OF ACNE

Document Type and Number:

WIPO Patent Application WO2002100420

Kind Code:

A3

Abstract:

A pharmaceutical composition is described, intended particularly for the treatment of acne, which includes a synergic association of erythromycin and a carrier based on zeolite brought to Zn form. This association formulated for topical application as a powder or as an ointment or paste. The preparation process is also described, which is based on an initial exchange of the ions present in the zeolite contained in rocks with Na<+> and a subsequent of sodium ions with Zn<2+>; this zeolite in zinc form is then mixed with erythromycin.

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Inventors:

DE GENNARO MAURIZIO (IT)
CERRI GUIDO (IT)
CARAMELLA CARLA MARCELLA (IT)
BONFERONI MARIA CRISTINA (IT)

Application Number:

PCT/EP2002/006275

Publication Date:

November 20, 2003

Filing Date:

June 07, 2002

Export Citation:

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Assignee:

UNIV NAPOLI FEDERICO II (IT)
UNIV PAVIA (IT)
DE GENNARO MAURIZIO (IT)
CERRI GUIDO (IT)
CARAMELLA CARLA MARCELLA (IT)
BONFERONI MARIA CRISTINA (IT)

International Classes:

A61K8/26; A61K8/27; A61K8/60; A61K9/14; A61K31/7048; A61K33/30; A61K35/02; A61P17/10; A61Q19/00; (IPC1-7): A61K33/30; A61K35/02; A61P17/10

Foreign References:

US4261982A

1981-04-14

Other References:

LI Y ET AL: "Ammoxidation of ethane - V. Solid-state ion exchange to prepare cobalt zeolite catalysts", APPLIED CATALYSIS A: GENERAL, ELSEVIER SCIENCE, AMSTERDAM, NL, vol. 188, no. 1-2, 5 November 1999 (1999-11-05), pages 211 - 217, XP004271998, ISSN: 0926-860X
IZUMI Y., URABE K., ONAKA M.: "Zeolite, clay and heteropoly acid in organic reactions", KODANSHA LTD /VCH, TOKYO/WEINHEIM, XP002220008
DATABASE WPI Derwent World Patents Index; AN 2000-678084, XP002220009, BELITSKII I.A. ET AL.: "Cosmetic composition"

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