PHENYLALANINE DERIVATIVE - KYOWA HAKKO KOGYO KK

Title:

PHENYLALANINE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2003/089410

Kind Code:

A1

Abstract:

A phenylalanine derivative represented by the formula (I): (I) (wherein m and n are the same or different and each is 1 or 2; R² represents (un)substituted lower alkyl, etc.; R¹ represents (un)substituted lower alkyl, etc.; and R³, R⁴, R⁵, and R⁶ are the same or different and each is hydrogen, (un)substituted lower alkyl, oxo, etc.) or a pharmacologically acceptable salt of the derivative. They are useful as an &agr 4 integrin inhibitor.

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Inventors:

NAKASATO YOSHISUKE (JP)
OHTA KIMINORI (JP)
ARAI ERI (JP)
SAKU OSAMU (JP)
KUSAKA HIROKO (JP)
NAKANISHI SATOSHI (JP)
MANABE HARUHIKO (JP)
OGAWA AKIRA (JP)

Application Number:

PCT/JP2003/004970

Publication Date:

October 30, 2003

Filing Date:

April 18, 2003

Export Citation:

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Assignee:

KYOWA HAKKO KOGYO KK (JP)
NAKASATO YOSHISUKE (JP)
OHTA KIMINORI (JP)
ARAI ERI (JP)
SAKU OSAMU (JP)
KUSAKA HIROKO (JP)
NAKANISHI SATOSHI (JP)
MANABE HARUHIKO (JP)
OGAWA AKIRA (JP)

International Classes:

A61P1/04; A61P3/10; A61P9/10; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P37/00; A61P37/06; A61P43/00; C07D213/74; C07D241/08; C07K5/078; A61K38/00; (IPC1-7): C07D207/327; A61K31/40; A61K31/495; A61K31/496; A61K31/497; A61K31/498; A61K31/506; A61K31/535; A61K31/551; A61K38/05; A61P1/04; A61P3/10; A61P9/10; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P37/00; A61P37/06; A61P43/00; C07D213/81; C07D213/82; C07D213/89; C07D215/36; C07D241/44; C07D257/02; C07D271/113; C07D285/08; C07D295/155; C07D295/185; C07D295/192; C07D295/215; C07D295/26; C07D307/68; C07D319/06; C07D401/12; C07D487/04; C07K5/065

Domestic Patent References:

WO2001036376A1

2001-05-25

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