Title:
POLYNUCLEOTIDES AND POLYPEPTIDES AS WELL AS METHODS FOR DIAGNOSING AND TREATING LUNG CANCER
Document Type and Number:
WIPO Patent Application WO2001072775
Kind Code:
A3
Abstract:
The present invention provides polynucleotides and polypeptides which are diagnostic markers for lung cancer. In addition, antibodies immunospecific for these markers are provided. Vectors, hosts cells and methods for producing these markers, as well as methods and tools for using these markers in detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating lung cancer are also provided.
Inventors:
CHEN SEI-YU (US)
HU PING (US)
RECIPON HERVE (US)
MACINA ROBERTO A (US)
HU PING (US)
RECIPON HERVE (US)
MACINA ROBERTO A (US)
Application Number:
PCT/US2001/010051
Publication Date:
August 22, 2002
Filing Date:
March 29, 2001
Export Citation:
Assignee:
DIADEXUS INC (US)
CHEN SEI-YU (US)
HU PING (US)
RECIPON HERVE (US)
MACINA ROBERTO A (US)
CHEN SEI-YU (US)
HU PING (US)
RECIPON HERVE (US)
MACINA ROBERTO A (US)
International Classes:
A61P35/00; C07K14/47; C12N15/12; A61K38/00; (IPC1-7): C12N15/12; C12N5/10; C07K14/47; C07K16/18; C12Q1/68; A61P35/00; A61K39/395; G01N33/574
Domestic Patent References:
| WO1999060160A1 | 1999-11-25 | |||
| WO2000012758A1 | 2000-03-09 | |||
| WO1999050278A1 | 1999-10-07 |
Other References:
HIBI ET AL: "Serial analysis of gene expression in non-small cell lung cancer", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 58, no. 24, December 1998 (1998-12-01), pages 5690 - 5690A,5691-5694, XP002925223, ISSN: 0008-5472
DATABASE INTERNET 19 April 2000 (2000-04-19), FITZPATRICK; WYSIWYG://125/HTTP://JAMA.AMA-A...ES/V283N15/FFULL/JMN0419-3.HTML; PAGES 1-2: "Japanese develop early test for lung cancer metastases", XP002193609
PETERSEN ET AL: "Gene expression profiling of advanced lung cancer", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 86, no. 4, 15 May 2000 (2000-05-15), pages 512 - 517, XP002166298, ISSN: 0020-7136
DATABASE INTERNET 19 April 2000 (2000-04-19), FITZPATRICK; WYSIWYG://125/HTTP://JAMA.AMA-A...ES/V283N15/FFULL/JMN0419-3.HTML; PAGES 1-2: "Japanese develop early test for lung cancer metastases", XP002193609
PETERSEN ET AL: "Gene expression profiling of advanced lung cancer", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 86, no. 4, 15 May 2000 (2000-05-15), pages 512 - 517, XP002166298, ISSN: 0020-7136
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