Title:
PREPARATION METHOD OF L-NICOTINE
Document Type and Number:
WIPO Patent Application WO/2022/222914
Kind Code:
A1
Abstract:
The present invention provides a preparation method for L-nicotine, the method can obtain L-nicotine having an optical purity of more than 99.9%, which is much higher than that of similar products in the current market. The total yield of synthesis reaches 50-60%. The reaction materials are cheap and easy to obtain. The operation is simple, environmentally friendly, and is suitable for large-scale industrial production.
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Inventors:
SHEN LITAO (CN)
LIU YAOXIU (CN)
GU LIMIN (CN)
LIU YAOXIU (CN)
GU LIMIN (CN)
Application Number:
PCT/CN2022/087601
Publication Date:
October 27, 2022
Filing Date:
April 19, 2022
Export Citation:
Assignee:
HUANGGANG ZY BIOTECHNOLOGY CO LTD (CN)
WUHAN ZY PHARMACEUTICALS CO LTD (CN)
WUHAN QR PHARMACEUTICALS CO LTD (CN)
WUHAN ZY PHARMACEUTICALS CO LTD (CN)
WUHAN QR PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D401/04; C07B53/00
Domestic Patent References:
| WO2019121649A1 | 2019-06-27 | |||
| WO2012001644A1 | 2012-01-05 |
Foreign References:
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| CN102143968A | 2011-08-03 | |||
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Other References:
TRAN GAËL, SHAO WEN, MAZET CLÉMENT: "Ni-Catalyzed Enantioselective Intermolecular Hydroamination of Branched 1,3-Dienes Using Primary Aliphatic Amines", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 141, no. 37, 18 September 2019 (2019-09-18), pages 14814 - 14822, XP055979121, ISSN: 0002-7863, DOI: 10.1021/jacs.9b07253
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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