Title:
REGULATION OF HUMAN FGD1-LIKE PROTEIN
Document Type and Number:
WIPO Patent Application WO2002024731
Kind Code:
A3
Abstract:
Reagents which regulate human FGD1-like protein and reagents which bind to human FGD1-like gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer and obesity.
Inventors:
KOSSIDA SOPHIA (FR)
Application Number:
PCT/EP2001/011009
Publication Date:
July 25, 2002
Filing Date:
September 24, 2001
Export Citation:
Assignee:
BAYER AG (DE)
KOSSIDA SOPHIA (FR)
KOSSIDA SOPHIA (FR)
International Classes:
C07K14/47; A61K38/00; (IPC1-7): C07K14/47; A61K31/713; A61K39/395; C07K16/18; C12N5/10; C12N15/10; C12N15/62; C12Q1/68; G01N33/50; G01N33/68
Foreign References:
| EP1074617A2 | 2001-02-07 |
Other References:
PASTERIS N GERMAN ET AL: "Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: A putative Rho/Rac guanine nucleotide exchange factor.", CELL, vol. 79, no. 4, 1994, pages 669 - 678, XP002196270, ISSN: 0092-8674
ZHENG YI ET AL: "The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 52, 1996, pages 33169 - 33172, XP002196271, ISSN: 0021-9258
DATABASE EMBL [online] EBI, Hinxton UK; 22 February 2000 (2000-02-22), ISOGAI ET AL.: "Homo sapiens cDNA FLJ11183 fis, clone PLACE1007488, weakly similar to", XP002196275, Database accession no. AK002045
DATABASE EMBL [online] EBI, Hinxton, UK; 14 March 2000 (2000-03-14), OHARA ET AL.: "Homo sapiens mRNA for KIAA1362 protein, partial cds.", XP002196276, Database accession no. AB037783
DATABASE GENSEQ [online] Derwent; 26 June 2001 (2001-06-26), OTA ET AL.: "Protein Seq Id: 12972 from patent EP1074617", XP002196273, Database accession no. AAB93568
DATABASE GENSEQ [online] Derwent; 26 June 2001 (2001-06-26), OTA ET AL.: "Human cDNA sequence SEQ ID NO:12971 from patent EP1074617", XP002196274, Database accession no. AAH15014
OLSON M F: "Guanine nucleotide exchange factors for the Rho GTPases: A role in human disease?", JOURNAL OF MOLECULAR MEDICINE (BERLIN), vol. 74, no. 10, 1996, pages 563 - 571, XP002196272, ISSN: 0946-2716
ZHENG YI ET AL: "The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 52, 1996, pages 33169 - 33172, XP002196271, ISSN: 0021-9258
DATABASE EMBL [online] EBI, Hinxton UK; 22 February 2000 (2000-02-22), ISOGAI ET AL.: "Homo sapiens cDNA FLJ11183 fis, clone PLACE1007488, weakly similar to", XP002196275, Database accession no. AK002045
DATABASE EMBL [online] EBI, Hinxton, UK; 14 March 2000 (2000-03-14), OHARA ET AL.: "Homo sapiens mRNA for KIAA1362 protein, partial cds.", XP002196276, Database accession no. AB037783
DATABASE GENSEQ [online] Derwent; 26 June 2001 (2001-06-26), OTA ET AL.: "Protein Seq Id: 12972 from patent EP1074617", XP002196273, Database accession no. AAB93568
DATABASE GENSEQ [online] Derwent; 26 June 2001 (2001-06-26), OTA ET AL.: "Human cDNA sequence SEQ ID NO:12971 from patent EP1074617", XP002196274, Database accession no. AAH15014
OLSON M F: "Guanine nucleotide exchange factors for the Rho GTPases: A role in human disease?", JOURNAL OF MOLECULAR MEDICINE (BERLIN), vol. 74, no. 10, 1996, pages 563 - 571, XP002196272, ISSN: 0946-2716
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