Title:
SINGLE DOMAIN ANTIBODY TARGETING HUMAN ROR1
Document Type and Number:
WIPO Patent Application WO/2024/094159
Kind Code:
A1
Abstract:
Provided in the present application are a single domain antibody targeting the ROR1 protein as well as a chimeric antigen receptor (CAR) and CAR-T cell comprising the single domain antibody. Also provided are uses of the single domain antibody and CAR-T cell in the treatment of tumors expressing the ROR1 protein.
More Like This:
| WO/2022/187275 | ANTIBODIES AGAINST CLAUDIN-6 AND USES THEREOF |
| JP2022002546 | CELL |
| JP6625106 | B7-DC binding antibody |
Inventors:
LI YINGYU (CN)
JIA WENSHUANG (CN)
QI ZENG (CN)
XIN YANG (CN)
LI LIANQU (CN)
ZHOU YI (CN)
CHEN LI (CN)
JIA WENSHUANG (CN)
QI ZENG (CN)
XIN YANG (CN)
LI LIANQU (CN)
ZHOU YI (CN)
CHEN LI (CN)
Application Number:
PCT/CN2023/129542
Publication Date:
May 10, 2024
Filing Date:
November 03, 2023
Export Citation:
Assignee:
NANJING PROBIO BIOTECH CO LTD (CN)
International Classes:
C07K16/30; A61K39/395; A61P35/00; C07K19/00; C12N5/0783; C12N5/10; C12N15/13; C12N15/62; C12N15/63
Foreign References:
| CN107428833A | 2017-12-01 | |||
| CN108707619A | 2018-10-26 | |||
| CN114539411A | 2022-05-27 | |||
| CN109836498A | 2019-06-04 | |||
| CN114929751A | 2022-08-19 |
Attorney, Agent or Firm:
CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE (CN)
Download PDF: