Title:
SUBSTITUTED CYCLOALKYLS AS MODULATORS OF THE INTEGRATED STRESS PATHWAY
Document Type and Number:
WIPO Patent Application WO/2020/223538
Kind Code:
A8
Abstract:
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.
Inventors:
MARTIN KATHLEEN (US)
SIDRAUSKI CARMELA (US)
SHI LEI (US)
MURAUSKI KATHLEEN (US)
XU XIANGDONG (US)
TONG YUNSONG (US)
RANDOLPH JOHN (US)
DART MICHAEL (US)
BENELKEBIR HANAE (GB)
EDESON STEVEN (GB)
STARBUCK KATHRYN (GB)
SIDRAUSKI CARMELA (US)
SHI LEI (US)
MURAUSKI KATHLEEN (US)
XU XIANGDONG (US)
TONG YUNSONG (US)
RANDOLPH JOHN (US)
DART MICHAEL (US)
BENELKEBIR HANAE (GB)
EDESON STEVEN (GB)
STARBUCK KATHRYN (GB)
Application Number:
PCT/US2020/030819
Publication Date:
November 18, 2021
Filing Date:
April 30, 2020
Export Citation:
Assignee:
CALICO LIFE SCIENCES LLC (US)
ABBVIE INC (US)
ABBVIE INC (US)
International Classes:
C07D311/74; A61P25/00; A61P35/00; A61P37/00; C07C1/00; C07D213/53; C07D265/36; C07D271/10; C07D405/06; C07D405/12; C07D405/14; C07D407/12; C07D413/04; C07D413/12; C07D417/12
Attorney, Agent or Firm:
MCCARTY, Catherine, M. et al. (US)
Download PDF: