Title:
TEST STRIP FOR DETERMINING CONCENTRATION OF MULTIPLE ANALYTES IN A SINGLE FLUID SAMPLE
Document Type and Number:
WIPO Patent Application WO2003058252
Kind Code:
A3
Abstract:
A multilayer test strip [20] that measures concentrations of multiple analytes from a single whole blood sample [58]. The test strip [201 includes a test matrix [36] of several layers held together in constant contact by a test strip holder [22]. The invention is characterized in that it has no moving parts, which is made possible by the novel use of an elongate disbursement layer [38] that spreads blood throughout its entire length, despite having layers [40, 110] with known wicking properties adjacent to and in contact with it [38]. Since the invention relies primarily on a vertical flow format, the test strip [20] is advantageously quite compact. With a single 35 microliter sample [58] of blood applied thereto, the novel test strip [20] can provide readings of total cholesterol, HDL cholesterol and triglycerides. From these, LDL can be calculated, thereby providing a full "lipid panel." Other analytes such as glucose and ketoses may be included in the test strip [20] in addition to or in lieu of one or more of the other analytes.
Inventors:
ANAOKAR SUNIL
CRISPINO MICHELLE JEANNE
CRABTREE EMANUEL PAUL
CRISPINO MICHELLE JEANNE
CRABTREE EMANUEL PAUL
Application Number:
PCT/US2002/041672
Publication Date:
August 05, 2004
Filing Date:
December 30, 2002
Export Citation:
Assignee:
POLYMER TECHNOLOGY SYSTEMS INC (US)
ANAOKAR SUNIL
CRISPINO MICHELLE JEANNE
CRABTREE EMANUEL PAUL
ANAOKAR SUNIL
CRISPINO MICHELLE JEANNE
CRABTREE EMANUEL PAUL
International Classes:
C12Q1/44; G01N33/543; G01N33/92; (IPC1-7): G01N33/92; G01N33/52; G01N33/49; C12Q1/60
Foreign References:
| US5962215A | 1999-10-05 | |||
| EP1028319A2 | 2000-08-16 | |||
| US5597532A | 1997-01-28 | |||
| US5135716A | 1992-08-04 | |||
| US5637469A | 1997-06-10 |
Download PDF: