Title:
TOCOPHEROL AND TOCOTRIENOL MEDICAMENTS
Document Type and Number:
WIPO Patent Application WO2004047732
Kind Code:
A3
Abstract:
Anti-inflammatory compositions include medicaments comprising predetermined amounts of a phytyl substituted chromanol and a prostaglandin E2 inhibitor, wherein: said medicament is in unit dosage form suitable for pharmaceutical administration; said phytyl substituted chromanol is a gamma-tocopherol, delta-tocopherol, gamma-tocotrienol or delta-tocotrienol; said PGE2 inhibitor is a non-steroidal anti-inflammatory drug or an omega-3 fatty acid, such as docosahexaenoic acid and eicosapentaenoic acid. Anti-obesity compositions include medicaments comprising predetermined amounts of a phytyl substituted chromanol and an obesity-promoting drug, wherein: said medicament is in unit dosage form suitable for pharmaceutical administration; said phytyl substituted chromanol is a gamma-tocopherol, delta-tocopherol, alpha-tocotrienol, gamma-tocotrienol or delta-tocotrienol; said obesity-promoting drug is a corticosteroid or an anti-diabetes drug such as a hypoglycemic drug, starch blocker, glucose production blocker or insulin sensitizer.
Inventors:
AMES BRUCE N
JIANG QING
JIANG QING
Application Number:
PCT/US2003/037135
Publication Date:
August 19, 2004
Filing Date:
November 19, 2003
Export Citation:
Assignee:
CHILDRENS HOSP & RES CT OAK (US)
International Classes:
A61K31/155; A61K31/202; A61K31/355; A61K31/426; A61K31/4439; A61K31/56; A61K31/70; A61K45/06; (IPC1-7): A61K31/355; A61K31/20; A61K31/353
Foreign References:
| US20030144219A1 | 2003-07-31 | |||
| US20030007961A1 | 2003-01-09 | |||
| US20030013693A1 | 2003-01-16 | |||
| US20030100603A1 | 2003-05-29 | |||
| US20020032171A1 | 2002-03-14 |
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