TRANSIENT EXPRESSION VECTORS, PREPARATION AND USES THEREOF

WIPO Patent Application WO/2013/060819

A3

The present invention describes a recombinant retroviral vector which cannot by itself achieve complete reverse transcription as well as its uses, in particular for transiently transferring in vitro, ex vivo or in vivo at least one ribonucleic acid sequence of interest in a cell. Such a transient transgene expression is of interest in the context of research, therapy and more generally in the field of biotechnology.

JP2002512985	INDUSTRIAL APPLICABILITY A method for delivering a polynucleotide to a cell via the vascular system.
WO/2001/092508	PSEUDO-TYPE RETROVIRUS VECTOR CONTAINING MEMBRANE PROTEIN HAVING HEMAGGLUTININ ACTIVITY
WO/1999/051755	RIBOZYME-MEDIATED CONTROL OF GENE EXPRESSION

SARKIS CHAMSY (FR)
ALTEMIR DOROTHEE (FR)
GRANDCHAMP NICOLAS (FR)
PHILIPPE STEPHANIE (FR)

PCT/EP2012/071216

July 18, 2013

October 26, 2012

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NEWVECTYS (FR)

C12N15/867

WO2005116225A1

2005-12-08

JULIAS J G ET AL: "Replication of phenotypically mixed human immunodeficiency virus type 1 virions containing catalytically active and catalytically inactive reverse transcriptase.", JOURNAL OF VIROLOGY, vol. 75, no. 14, July 2001 (2001-07-01), pages 6537 - 6546, XP002671177, ISSN: 0022-538X
SHARMA PREM L ET AL: "Retrovirus reverse transcriptases containing a modified YXDD motif.", ANTIVIRAL CHEMISTRY & CHEMOTHERAPY, vol. 16, no. 3, 2005, pages 169 - 182, XP002671178, ISSN: 0956-3202

STARCK-LOUDES, Anne-Caroline et al. (25 rue Louis le Grand, Paris, FR)

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