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Title:
USE OF POLYPEPTIDE HAVING SUPEROXIDE DISMUTASE ACTIVITY AND EXTRACELLULAR VESICLES FOR TREATMENT OR PREVENTION OF RESPIRATORY VIRAL INFECTION
Document Type and Number:
WIPO Patent Application WO/2022/108424
Kind Code:
A1
Abstract:
The present invention relates to use of a polypeptide having superoxide dismutase (SOD) activity and/or extracellular vesicles containing SOD, for the prevention and/or treatment of respiratory viral infection or diseases caused by respiratory viral infection in a subject. The present invention also relates to use of a polypeptide having SOD activity derived from a Bacillus amyloliquefaciens strain and/or extracellular vesicles containing SOD derived from a Bacillus subtillis strain, for the prevention and/or treatment of respiratory viral infection or diseases caused by respiratory viral infection in a subject.

Inventors:
PAN JAE GU (KR)
KIM EUI JOONG (KR)
KIM JEONG HYUN (KR)
Application Number:
PCT/KR2021/017304
Publication Date:
May 27, 2022
Filing Date:
November 23, 2021
Export Citation:
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Assignee:
GENOFOCUS CO LTD (KR)
International Classes:
A61K38/16; A23L33/195; A61K9/00; A61P31/14
Foreign References:
KR101762199B12017-07-28
KR20200027624A2020-03-13
KR101762199B12017-07-28
Other References:
WYDE PHILIP R.; MOORE DONNA K.; MILES PIMENTEL D.; GILBERT BRIAN E.; NIMROD RAMI; PANET AMOS: "Recombinant superoxide dismutase (SOD) administered by aerosol inhibits respiratory syncytial virus infection in cotton rats", ANTIVIRAL RESEARCH, vol. 31, no. 3, 1 January 1900 (1900-01-01), NL , pages 173 - 184, XP029204487, ISSN: 0166-3542, DOI: 10.1016/0166-3542(95)06967-4
QIN MENG, CAO ZHENG, WEN JING, YU QINGSONG, LIU CHAOYONG, WANG FANG, ZHANG JIANJUN, YANG FENGMEI, LI YANYAN, FISHBEIN GREGORY, YAN: "An Antioxidant Enzyme Therapeutic for COVID‐19", ADVANCED MATERIALS, vol. 32, no. 43, 1 October 2020 (2020-10-01), DE , pages 1 - 9, XP055844371, ISSN: 0935-9648, DOI: 10.1002/adma.202004901
ILIC MARIJA, MAIER JULIAN, HOLY MARION, JAENTSCH KATHRIN, LIECHTI MATTHIAS E., LUBEC GERT, BAUMANN MICHAEL H., SITTE HARALD H., LU: "Cell-Based Radiotracer Binding and Uptake Inhibition Assays: A Comparison of In Vitro Methods to Assess the Potency of Drugs That Target Monoamine Transporters", FRONTIERS IN PHARMACOLOGY, vol. 11, 15 March 2022 (2022-03-15), CH , pages 1 - 11, XP055923007, ISSN: 1663-9812, DOI: 10.3389/fphar.2020.00673
BRADFORD M, ANAL BIOCHEM, vol. 72, 1976, pages 248 - 254
Attorney, Agent or Firm:
FIRSTLAW P.C. (KR)
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