Title:
MDM2とp53の間の相互作用の阻害剤
Document Type and Number:
Japanese Patent JP2010539220
Kind Code:
A
Abstract:
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds:wherein n, m, p, s, t, R1, R2, R3, R4, R5, R6, R7, R20, X, Y, Q and Z have defined meanings.
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Inventors:
Poncelet, Birjini Sofui
Coupa, Sofui
Stork, Pierre-Henri
Bryon, Brno
Coupa, Sofui
Stork, Pierre-Henri
Bryon, Brno
Application Number:
JP2010525346A
Publication Date:
December 16, 2010
Filing Date:
September 18, 2008
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D401/12; A61K31/435; A61K31/4439; A61K31/4709; A61K31/5377; A61K31/55; A61P35/00; A61P35/02; A61P43/00; C07D487/04
Domestic Patent References:
| JP2009531321A | 2009-09-03 | |||
| JP2004532209A | 2004-10-21 | |||
| JP2007522210A | 2007-08-09 |
Foreign References:
| WO2001042224A1 | 2001-06-14 | |||
| WO2006089286A2 | 2006-08-24 | |||
| WO2006136606A2 | 2006-12-28 | |||
| WO2009019274A1 | 2009-02-12 | |||
| WO2006032631A1 | 2006-03-30 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office