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Title:
テトラゾールの製法
Document Type and Number:
Japanese Patent JP4108744
Kind Code:
B2
Abstract:
The invention relates to a process for the preparation of N-protected 4-methyl-2'--(5H-tetrazolyl)biphenyl of formula (I), in which R is a tetrazole protective group, wherein a compound of formula (II), in which R is a tetrazole protective group, is reacted with a compound of formula (III') in which Hal is halogen, in the presence of a transition metal catalyst, to novel compounds of formula (I) and their use, and to novel intermediates.

Inventors:
Zergeny, Janos
Application Number:
JP51429596A
Publication Date:
June 25, 2008
Filing Date:
October 23, 1995
Export Citation:
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Assignee:
Novartis Akchen Gezel Shaft
International Classes:
C07D257/04; A61K31/41; A61P9/12; C07B61/00
Domestic Patent References:
JP5271205A
JP6192170A
JP6234690A
JP4253949A
JP5279350A
JP4225966A
JP3074369A
Foreign References:
WO1993010106A1
Other References:
R. N. Butler et al., Journal of the Chemical Society Perkin Transactions I, 1981年, p.390-393
社団法人日本化学会, 第4版 実験化学講座25 有機合成VII-有機金属試薬による合成-, 丸善株式会社, 1991年 9月 5日, p.390-392
Attorney, Agent or Firm:
Takashi Ishida
Kazuhiro Nakamura
Toshio Toda
Masaya Nishiyama