改善された特性を有するヒダントイナーゼ変異体及びそのアミノ酸の製造のための使用

Title:

改善された特性を有するヒダントイナーゼ変異体及びそのアミノ酸の製造のための使用

Document Type and Number:

Japanese Patent JP4641100

Kind Code:

B2

Abstract:

Hydantoinase enzymes are mutants of a previously isolated hydantoinase having the amino acid SEQ. ID. NO. 2. The mutants include amino acids substitutions at positions (95, 154, 180, 251 and/or 255) of the wild type hyndantoinase (SEQ. ID. NO. 2). The mutant hydantoinases, like the parent hydantoinase, are used in the production of optically pure amino acids.

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Inventors:

Francis H Arnold
Oliver May
Karl Heinz Drouts
Andreas Bomarius

Application Number:

JP2000608730A

Publication Date:

March 02, 2011

Filing Date:

March 28, 2000

Export Citation:

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Assignee:

California Institute of Technology

International Classes:

C12N15/09; C07H21/04; C12N1/15; C12N1/19; C12N1/20; C12N1/21; C12N5/10; C12N9/78; C12N9/86; C12N15/00; C12N15/63; C12N15/70; C12N15/74; C12P13/04; C12P13/06; C12P13/08; C12P13/12; C12P41/00; C12R1/19

Domestic Patent References:

JP7163347A
JP8322557A

Other References:

米国国立バイオテクノロジー情報センター(NCBI), Accession No. P81006, 01-FEB-1998 uploaded, [検索日:2009.8.26],URL,http://www.ncbi.nlm.nih.gov/sviewer/viewer.fcgi?3122243:OLDID:5251185

Attorney, Agent or Firm:

Takuya Kuno
Toshio Yano
Einzel Felix-Reinhard

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