Title:
【発明の名称】結腸特異的遺伝子およびタンパク質
Document Type and Number:
Japanese Patent JPH11506920
Kind Code:
A
Abstract:
Human colon specific gene polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides or polypeptides as a diagnostic marker for colon cancer and as an agent to determine if colon cancer has metastasized. Also disclosed are antibodies specific to the colon specific gene polypeptides which may be used to target cancer cells and be used as part of a colon cancer vaccine. Methods of screening for agonists and antagonists for the polypeptide and therapeutic uses of the antagonists are also disclosed.
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Inventors:
Soppet, Daniel Earl
Lee
Dillon, Patrick Jay
Lee
Dillon, Patrick Jay
Application Number:
JP50036597A
Publication Date:
June 22, 1999
Filing Date:
June 06, 1995
Export Citation:
Assignee:
HUMAN GENOME SCIENCES, INC.
International Classes:
G01N33/566; A61K31/70; A61K38/00; A61K39/395; A61K45/00; A61K48/00; A61P1/16; A61P35/00; C07K14/47; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12P21/08; C12Q1/68; G01N33/574; C12R1/19; C12R1/91; (IPC1-7): C12N15/09; A61K31/70; A61K38/00; A61K39/395; A61K45/00; A61K48/00; C07K14/47; C12N1/21; C12N5/10; C12P21/02; C12Q1/68; G01N33/566
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)