Title:
抗ＩｇＭ／Ｂ細胞表面抗原二重特異性抗体
Document Type and Number:
Japanese Patent JPWO2018174274
Kind Code:
A1
Abstract:
血中の分泌型ＩｇＭ存在下であっても、Ｂ細胞表面の膜結合型ＩｇＭとの結合活性が高く、Ｂ細胞に対し増殖阻害効果を発揮する抗体の提供。ＩｇＭ及びＢ細胞表面抗原に結合する二重特異性抗体。
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Inventors:
Yasuka Tsukada
Takahiro Ohashi
Hitoshi Miyashita
Satoko Takebe
Enonami Junpei
Takahiro Ohashi
Hitoshi Miyashita
Satoko Takebe
Enonami Junpei
Application Number:
JP2019507041A
Publication Date:
January 23, 2020
Filing Date:
March 23, 2018
Export Citation:
Assignee:
ZENYAKU KOGYO KABUSHIKI KAISHA
International Classes:
C07K16/46; A61K39/395; A61P35/00; A61P43/00; C07K16/28; C07K16/42
Other References:
THE JOURNAL OF IMMUNOLOGY, vol. 170, JPN6021048873, 2003, pages 2695 - 2701, ISSN: 0004656830
THE JOURNAL OF IMMUNOLOGY, vol. 173, JPN6021048875, 2004, pages 4736 - 4743, ISSN: 0004656831
THE JOURNAL OF IMMUNOLOGY, vol. 175, JPN6021048877, 2005, pages 6143 - 6154, ISSN: 0004656832
THE JOURNAL OF IMMUNOLOGY, vol. 173, JPN6021048875, 2004, pages 4736 - 4743, ISSN: 0004656831
THE JOURNAL OF IMMUNOLOGY, vol. 175, JPN6021048877, 2005, pages 6143 - 6154, ISSN: 0004656832
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation