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Title:
1,3,5-トリ置換されたトリアゾール誘導体
Document Type and Number:
Japanese Patent JP2011500624
Kind Code:
A
Abstract:
The present invention relates to 2-[3-(2,2-Difluoro-benzo[1,3]dioxol-5-ylamino)-5-(2,6-dimethyl-pyridin-4-yl)-[1,2,4]triazol-1-yl]-N-ethyl-acetamide and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to a potent positive allosteric modulator of nicotinic acetylcholine receptors which have the capability of increasing the efficacy of nicotinic receptor agonists.

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Inventors:
Touring, Johannes Wilhelms Jiyon Ef
Deincro, Theodorus
Roussajyu, Anne Simone Giosephine
Application Number:
JP2010529360A
Publication Date:
January 06, 2011
Filing Date:
October 15, 2008
Export Citation:
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Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D405/14; A61K31/4439; A61K45/00; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/34; A61P29/00; A61P43/00; C07B61/00
Domestic Patent References:
JP2006515313A2006-05-25
JP2009534357A2009-09-24
Foreign References:
WO2007031440A22007-03-22
WO2003094831A22003-11-20
WO2006078621A22006-07-27
Attorney, Agent or Firm:
Patent business corporation Odashima patent office



 
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