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Title:
血小板を用いるミクロ及びナノ粒子の送達
Document Type and Number:
Japanese Patent JP2010534193
Kind Code:
A
Abstract:
The invention is directed to platelets containing micron or nanometer size particles wherein the micron or nanometer sized particles comprises an active agent. The invention is also directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and the above platelets. The invention is further directed to methods of delivering the micron or nanometer size particles containing an active agent to a site of interest in a patient.

Inventors:
Fisher, Thomas, H.
Eskridge, Stan, E., Jr.
Application Number:
JP2010508365A
Publication Date:
November 04, 2010
Filing Date:
May 02, 2008
Export Citation:
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Assignee:
Entegrion, Inc.
International Classes:
A61K35/14; A61K35/19; A61K38/16; A61K45/00; A61K47/48; A61P7/04; A61P9/00; A61P35/00; A61P43/00; C12N5/078; A61K35/12
Domestic Patent References:
JP2006525810A2006-11-16
JPH08109142A1996-04-30
Other References:
JPN6013013495; Ｊｏｈａｎｓｓｏｎ　ＬＯ，　ｅｔ　ａｌ．: 'Ａ　ｔａｒｇｅｔｅｄ　ｃｏｎｔｒａｓｔ　ａｇｅｎｔ　ｆｏｒ　ｍａｇｎｅｔｉｃ　ｒｅｓｏｎａｎｃｅ　ｉｍａｇｉｎｇ　ｏｆ　ｔｈｒｏｍｂｕｓ：　Ｉｍｐｌｉｃａｔｉｏｎｓ　ｏｆ　ｓｐａｔｉａｌ　ｒｅｓｏｌｕ' Ｊｏｕｒｎａｌ　ｏｆ　Ｍａｇｎｅｔｉｃ　Ｒｅｓｏｎａｎｃｅ　Ｉｍａｇｉｎｇ Ｖｏｌ．　１３，　Ｎｏ．　４, 200104, ｐ．　６１５-６１８
JPN6013013496; Ｓｃｕｌｌ　ＣＭ，　ｅｔ　ａｌ．: 'Ｇｅｎｅ　Ｔｒａｎｓｆｅｒ　ｔｏ　Ｍａｃｒｏｐｈａｇｅｓ　ｗｉｔｈ　Ｎａｎｏｐａｒｔｉｃｌｅ-Ｌｏａｄｅｄ　Ｐｌａｔｅｌｅｔｓ' Ｂｌｏｏｄ　（ＡＳＨ　Ａｎｎｕａｌ　Ｍｅｅｔｉｎｇ　Ａｂｓｔｒａｃｔｓ）　［ｏｎｌｉｎｅ］ Ｖｏｌ．　１０６，　Ｎｏ．　１１, 2005, Ａｂｓｔｒａｃｔ　３０４３
JPN6013013498; Ａｉ　Ｈ，　ｅｔ　ａｌ．: 'Ｅｌｅｃｔｒｏｓｔａｔｉｃ　ｌａｙｅｒ-ｂｙ-ｌａｙｅｒ　ｎａｎｏａｓｓｅｍｂｌｙ　ｏｎ　ｂｉｏｌｏｇｉｃａｌ　ｍｉｃｒｏｔｅｍｐｌａｔｅｓ：　ｐｌａｔｅｌｅｔｓ' Ｂｉｏｍａｃｒｏｍｏｌｅｃｕｌｅｓ Ｖｏｌ．　３，　Ｎｏ．　３, 200205, ｐ．　５６０-５６４
Attorney, Agent or Firm:
Asamura patent office
Hideto Asamura
Hajime Asamura
Yoshitaka Watanabe
Naganuma Akio
Yukihiro Ikeda
Kajiwara Saiko
Shinmura Morio
Kanamori Koji
Yuko Nagase
Youichi Inoue
Mari Yuge



 
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