Title:
EYE-DROPS CONTAINING TWO OR MORE COMPONENTS
Document Type and Number:
Japanese Patent JP2015067607
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide eye-drops, in which the precipitation generation under cold conditions and the stability of allantoin are improved, containing tetrahydrozoline or a salt thereof, neostigmine or a salt thereof, allantoin, glycyrrhizinic acid or a salt thereof, zinc sulfate hydrate, chlorpheniramine or a salt thereof, vitamin B12, vitamin B6 or a salt thereof, panthenol, L-aspartic acid or a salt thereof, taurine and chondroitin sulfate ester or a salt thereof.SOLUTION: The invention provides eye-drops containing tetrahydrozoline or a salt thereof, neostigmine or a salt thereof, allantoin, glycyrrhizinic acid or a salt thereof, zinc sulfate hydrate, chlorpheniramine or a salt thereof, vitamin B12, vitamin B6 or a salt thereof, panthenol, L-aspartic acid or a salt thereof, taurine, chondroitin sulfate ester or a salt thereof, and a surfactant, controlling pH of 4.0-5.7. As the surfactant, polysorbate 80 is preferable.
Inventors:
ISHIDA KATSUSHI
OKURA KAZUKUNI
UKAI EIICHI
YAMAKAWA YUICHI
KUROIWA MANABU
OKURA KAZUKUNI
UKAI EIICHI
YAMAKAWA YUICHI
KUROIWA MANABU
Application Number:
JP2013215841A
Publication Date:
April 13, 2015
Filing Date:
September 27, 2013
Export Citation:
Assignee:
SHIGAKEN PHARM IND CO LTD
International Classes:
A61K33/30; A61K31/164; A61K31/185; A61K31/198; A61K31/27; A61K31/4164; A61K31/4166; A61K31/4402; A61K31/4415; A61K31/704; A61K31/714; A61K31/737; A61K47/34; A61P27/02