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Title:
胃癌バイオマーカー及びその用途
Document Type and Number:
Japanese Patent JP7345860
Kind Code:
B2
Abstract:
An object is to provide a highly practical, gastric cancer-specific, and minimally invasive biomarker. As gastric cancer biomarkers, hsa-miR-6807-5p, hsa-miR-6856-5p and hsa-miR-575 have been identified. The morbidity of gastric cancer is determined using expression levels of the microRNAs as an index.

Inventors:
Takaya Shimura
Hiroyasu Iwasaki
Application Number:
JP2020525409A
Publication Date:
September 19, 2023
Filing Date:
May 28, 2019
Export Citation:
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Assignee:
Public University Corporation Nagoya City University
International Classes:
C12N15/11; C12Q1/686; C12Q1/6886; G01N33/574
Domestic Patent References:
JP2017195803A
Other References:
YU, Y. et al.,MicroRNA profiling of human gastric cancer,Molecular Medicine Reports,2009年,Vol.2,pp.963-970,ISSN: 1791-3004, 特にAbstract
Agilent Technologies, Agilent-070156 Human_miRNA_V21.0_Microarray 046064 (gene name version) GEO,2018年03月16日,[検索日2023年3月20日],インターネット,
RAI, R.P. et al.,Elevated expression of miR-223 and miR-21 in Helicobacter pylori induced gastric cancer patients,17th International Congress on Infectious Diseases / International Journal of Infectious Diseases,2016年,Vol.45 Suppl.,p.147,ISSN: 1201-9712, 全文
HUANG, S. et al.,Serum microRNA expression profile as a diagnostic panel for gastric cancer,Japanese Journal of Clinical Oncology,2016年,Vol.46, No.9,pp.811-818,ISSN: 1465-3621, 特にAbstract, Figure 1-3, Table 3-4
ZHANG, C. et al.,Three-microRNA signature identified by bioinformatics analysis predicts prognosis of gastric cancer,World J. Gastroenterol.,2018年03月,Vol.24, No.11,pp.1206-1215,ISSN: 2219-2840, 特にAbstract
KAO, H.-W. et al.,Urine miR-21-5p as a potential non-invasive biomarker for gastric cancer,Oncotarget,2017年,Vol.8,pp.56389-56397,ISSN: 1949-2553, 特にAbstract
miRBase rel.21 に対応した SurePrint miRNA Microarrays rel. 21, [retrieved on 2019-08-08],Agilent Technology,2015年,全文,
Attorney, Agent or Firm:
Sumio Tanai
Masato Iida
Kazuzumi Nishizawa
Yuichiro Kawagoe