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Title:
METHOD FOR PRODUCING MIXED CRYSTAL OF TYPE I CRYSTAL AND TYPE II CRYSTAL OF ()2-(DIMETHYLAMINO)-1-{[O-(M-METHOXYPHENETHYL)PHENOXY]METHYL}ETHYLHYDROGEN SUCCINATE HYDROCHLORIDE
Document Type and Number:
Japanese Patent JP2010126447
Kind Code:
A
Abstract:

To provide a mixed crystal of type I crystal and type II crystal of ()2-(dimethylamino)-1-{[O-(m-methoxyphenethyl)phenoxy]methyl}ethylhydrogen succinate hydrochloride which is useful as a drug.

A solution of ()2-(dimethylamino)-1-{[O-(m-methoxyphenethyl)phenoxy]methyl}ethylhydrogen succinate hydrochloride and hydrogen chloride are mixed to obtain the mixed crystal of type I crystal and type II crystal of ()2-(dimethylamino)-1-{[O-(m-methoxyphenethyl)phenoxy]methyl}ethylhydrogen succinate hydrochloride.


Inventors:
OYAMA TETSUYA
OMOTE RYUICHI
IKEDA SHIN
SUZUKI YOSHINOBU
Application Number:
JP2008299573A
Publication Date:
June 10, 2010
Filing Date:
November 25, 2008
Export Citation:
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Assignee:
DNP FINE CHEMICALS FUKUSHIMA C
International Classes:
A61K31/138; A61P1/04; A61P9/00; A61P9/10; A61P25/04; A61P43/00
Domestic Patent References:
JP2008255065A2008-10-23
JP2006160764A2006-06-22
JP2008195654A2008-08-28
JP2008088157A2008-04-17
JP2008531511A2008-08-14
JP2005015486A2005-01-20



 
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