Title:
置換体活性化配列を有する修飾されたヘプシン分子及びその使用
Document Type and Number:
Japanese Patent JP2006507813
Kind Code:
A
Abstract:
The present invention provides modified hepsin molecules, or fragments or derivatives thereof, including those having a substitute activation sequence. The modified hepsin molecules are cleaved at the substitute activation sequence, thereby generating activated modified hepsin molecule, or fragments or derivatives thereof, that exhibit the functional activity of naturally-occurring, wild-type hepsin molecules.
Inventors:
Parry, Gordon
Vogel, david
Vitrou, mark
Woo, Chinyu
Vogel, david
Vitrou, mark
Woo, Chinyu
Application Number:
JP2004543082A
Publication Date:
March 09, 2006
Filing Date:
October 02, 2003
Export Citation:
Assignee:
Schering Actien Gezel Shaft
International Classes:
C12N15/09; A61K9/08; A61K9/107; A61K9/127; A61K9/28; A61K9/48; A61K38/48; A61K39/00; A61K39/395; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/26; A61K47/30; A61K47/42; A61K47/44; A61P35/00; A61P35/04; A61P43/00; C07K5/083; C07K5/087; C07K5/103; C07K16/30; C07K16/40; C07K16/42; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/64; C12N15/02; C12Q1/02; C12Q1/37; C12Q1/68; G01N33/573; G01N33/574; C12P21/08
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama