Title:
PRODUCTION OF PHYTONE AND ISOPHYTOL
Document Type and Number:
Japanese Patent JP3882245
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To industrially and advantageously produce the subject compound useful as a synthetic raw material for biologically active substances such as vitamin E by efficiently and simply producing 6-methyl-2-heptanone from isovaleral and acetone and using the compound as a raw material.
SOLUTION: Isovaleral is subjected to cross aldol condensation with acetone while continuously each adding isovaleral and an aqueous alkali solution to acetone to form 6-methyl-3-hepten-2-one and the compound is hydrogenated to form 6-methyl-2-heptanone and 6-methyl-2-heptanone is used as a raw material to finally form 6,10,14-trimethyl-5,9-pentadecadien-2-one, which is then hydrogenated to provide the objective phytone and the phytone is further reacted with a Grignard reagent to vinylate or ethynylate the phytone and the treated phytone is partially hydrogenated to provide the objective isophytol.
Inventors:
Youichi Kido
Noriaki Kumagai
Hideharu Iwasaki
Takashi Onishi
Ueyama Fuyu
Noriaki Kumagai
Hideharu Iwasaki
Takashi Onishi
Ueyama Fuyu
Application Number:
JP35221496A
Publication Date:
February 14, 2007
Filing Date:
December 11, 1996
Export Citation:
Assignee:
KURARAY CO.,LTD.
International Classes:
C07C29/145; C07C45/62; C07C33/03; C07C45/72; C07C49/04; C07C49/203; (IPC1-7): C07C33/03; C07C29/145; C07C45/62; C07C49/04
Domestic Patent References:
| JP49049912A | ||||
| JP55038389A | ||||
| JP32009062B1 | ||||
| JP54014906A | ||||
| JP8333295A | ||||
| JP54017905A | ||||
| JP54017906A | ||||
| JP56133235A | ||||
| JP46003045B1 | ||||
| JP50020049B1 | ||||
| JP52125104A | ||||
| JP10017521A | ||||
| JP49025251B1 | ||||
| JP38026657B1 |
Foreign References:
| US2809215 |
Other References:
FUJISHIMA,T. et al.,Archiv der Pharmazie,1996年,Vol.329, No.1,p.27-34
Attorney, Agent or Firm:
Taji U.S. Patent Office
Noboru Tajime
Tajime Keiko
Noboru Tajime
Tajime Keiko