Title:
RECOMBINANT VIRUS-LIKE PARTICLES CODED BY MULTI-GENE VECTOR
Document Type and Number:
Japanese Patent JP2016104015
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide new virus-like particles to be used as a vaccine, a diagnostic tool, and an R&D tool based on a recombinant DNA technique and a cell culture technique for producing a vaccine or the like.SOLUTION: Recombinant virus-like particles are assembled by a polypeptide chain which incorporated several which are particularly two or more different epitopes selected from any one of (a) different virus strains of the same virus, and/or (b) different serotypes of the same virus, and/or (c) different virus strains specific to different hosts. Then, the epitopes are displayed on a particle surface.SELECTED DRAWING: None
Inventors:
CORINNE JOHN
CHRISTIAN SCHAUB
SABINE WELLNITZ
CHRISTIAN SCHAUB
SABINE WELLNITZ
Application Number:
JP2015247572A
Publication Date:
June 09, 2016
Filing Date:
December 18, 2015
Export Citation:
Assignee:
PFIZER
International Classes:
C12N7/01; A61K35/17; A61K39/12; A61K39/145; A61K39/295; A61K47/42; A61K47/48; A61K49/00; A61P31/12; A61P31/16; A61P31/20; A61P37/04; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09
Domestic Patent References:
| JP2004501647A | 2004-01-22 | |||
| JP2007527722A | 2007-10-04 | |||
| JP2009511084A | 2009-03-19 | |||
| JP2007529997A | 2007-11-01 |
Foreign References:
| US20040224305A1 | 2004-11-11 | |||
| WO2007130330A2 | 2007-11-15 | |||
| WO2009012489A1 | 2009-01-22 | |||
| WO2010125201A1 | 2010-11-04 | |||
| WO2008094197A2 | 2008-08-07 |
Other References:
VIROLOGY, vol. 240, no. 2, JPN6014037667, 1998, pages 316 - 325, ISSN: 0003436334
VIROL. J., vol. 6, JPN6014037668, 6 January 2009 (2009-01-06), pages 2, ISSN: 0003436335
MMWR, MORBIDITY AND MORTALITY WEEKLY REPORT, vol. 57, no. 7, JPN6016039556, 2008, US, pages 1 - 60, ISSN: 0003591118
VIROL. J., vol. 6, JPN6014037668, 6 January 2009 (2009-01-06), pages 2, ISSN: 0003436335
MMWR, MORBIDITY AND MORTALITY WEEKLY REPORT, vol. 57, no. 7, JPN6016039556, 2008, US, pages 1 - 60, ISSN: 0003591118
Attorney, Agent or Firm:
Patent business corporation Tsukuni