Title:
REGULATORY T CELL EPITOPES
Document Type and Number:
Japanese Patent JP2023106434
Kind Code:
A
Abstract:
To provide compositions comprising regulatory T cell epitopes, where the epitopes comprise a polypeptide comprising at least a portion of a specific sequence, fragments thereof and/or variants thereof, as well as methods of producing and using the compositions.SOLUTION: The invention provides a T cell epitope composition comprising one or more isolated T cell epitope polypeptides. The invention also provides the use of the T cell epitope composition in production of a drug for suppressing an antigen-specific immune response to a target antigen in a subject, where at least one T cell epitope polypeptide is covalently bound, non-covalently bound, or mixed with the target antigen to reduce the immune response to the target antigen.SELECTED DRAWING: None
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Inventors:
WILLIAM MARTIN
AMY S ROSENBERG
AMY S ROSENBERG
Application Number:
JP2023075635A
Publication Date:
August 01, 2023
Filing Date:
May 01, 2023
Export Citation:
Assignee:
EPIVAX INC
FOOD AND DRUG ADMINISTRATION
FOOD AND DRUG ADMINISTRATION
International Classes:
C07K7/08; A61K38/08; A61K38/10; A61K39/00; A61K39/35; A61P37/02; A61P43/00; C07K7/06; C12N5/0783; C12Q1/02
Attorney, Agent or Firm:
Patent Attorney Corporation Asamura Patent Office
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