YNL 075W/HTXFT 19 POLYNUCLEOTIDE AND POLYPEPTIDE

Japanese Patent JPH1132782

A

To obtain the subject polypeptide being products from ortholog and functionally homologous types and useful for remedy and diagnosis assay, etc., of decreases in the bone density including osteoporosis, HIV-related cachexia and other immune insufficiency, inappetite, overeating and other diseases.

This polypeptide is HTXFT 19 polypeptide having an amino acid sequence at least 80% identical with the amino acid sequence of the formula and can be obtained according to an arbitrary suitable metod (gen recombinant production, etc.). The polynucotide encoding HTXFT 19 polypeptide is obtained from the cDNA library derived from mRNA in human endometrium tumor cells, human testis cells, etc., according to EST analyis.

DEMARINI DOUGLAS JAMES

JP2135498A

February 09, 1999

February 02, 1998

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SMITHKLINE BEECHAM CORP

G01N33/53; A61K31/70; A61K38/00; A61K39/12; A61K48/00; A61P1/04; A61P1/14; A61P3/02; A61P7/10; A61P9/00; A61P9/02; A61P9/08; A61P9/10; A61P9/12; A61P11/00; A61P11/08; A61P13/02; A61P15/00; A61P19/10; A61P25/00; A61P25/18; A61P25/20; A61P25/28; A61P31/04; A61P33/02; A61P35/00; A61P37/00; A61P37/04; A61P37/08; A61P43/00; C07K14/47; C07K16/18; C12N1/19; C12N1/21; C12N5/10; C12N15/00; C12N15/09; C12N15/12; C12P21/02; C12Q1/68; G01N33/531; G01N33/566; C12R1/91; (IPC1-7): C12N15/09; A61K31/70; A61K38/00; A61K39/12; A61K48/00; C07K14/47; C07K16/18; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/68; G01N33/53; G01N33/531; G01N33/566

Yusuke Hiraki (2 outside)

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