AMINOPHENYLPROPANOIC ACID DERIVATIVE

Title:

AMINOPHENYLPROPANOIC ACID DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2005/087710

Kind Code:

A1

Abstract:

A compound represented by the formula (1) (wherein the symbols are the same as defined in the description), a salt thereof, and a prodrug thereof. They unexpectedly have excellent GPR40 receptor agonistic activity and are excellent in properties required of medicines, such as stability. They can be a medicine which is safe and useful as a preventive/therapeutic agent for pathological states or diseases in which a GPR40 receptor participates, such as diabetes.

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Inventors:

YASUMA TSUNEO (JP)
NEGORO NOBUYUKI (JP)
SASAKI SHINOBU (JP)

Application Number:

PCT/JP2005/004872

Publication Date:

September 22, 2005

Filing Date:

March 14, 2005

Export Citation:

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Assignee:

TAKEDA PHARMACEUTICAL (JP)
YASUMA TSUNEO (JP)
NEGORO NOBUYUKI (JP)
SASAKI SHINOBU (JP)

International Classes:

A61K31/16; A61K31/195; A61K31/222; A61K31/337; A61K31/343; A61K31/382; A61K31/40; A61K31/4015; A61K31/404; A61K31/4152; A61K31/42; A61K31/426; A61K31/427; A61K31/44; A61K31/4439; A61K31/445; A61K31/47; A61K31/5375; A61P3/10; A61P43/00; C07C229/42; C07C233/18; C07C233/53; C07C235/06; C07C259/06; C07C309/66; C07C311/21; C07C311/51; C07C317/18; C07C317/32; C07C323/12; C07D207/27; C07D207/404; C07D209/08; C07D209/14; C07D211/46; C07D213/64; C07D213/69; C07D213/74; C07D213/76; C07D215/06; C07D215/12; C07D231/12; C07D231/22; C07D231/24; C07D261/08; C07D277/28; C07D295/18; C07D305/06; C07D307/79; C07D335/02; C07D401/12; C07D409/12; C07D417/12; C07F7/18; C07F9/40; (IPC1-7): C07C229/42; A61K31/16; A61K31/195; A61K31/222; A61K31/337; A61K31/343; A61K31/382; A61K31/40; A61K31/4015; A61K31/404; A61K31/4152; A61K31/42; A61K31/426; A61K31/427; A61K31/44; A61K31/4439; A61K31/445; A61K31/47; A61K31/5375; A61P3/10; A61P43/00; C07C233/18; C07C233/53; C07C235/06; C07C259/06; C07C309/66; C07C311/21; C07C311/51; C07C317/18; C07C317/32; C07C323/12; C07D207/27; C07D207/404; C07D209/08; C07D209/14; C07D211/46; C07D213/64; C07D213/69; C07D213/74; C07D213/76; C07D215/12; C07D231/12; C07D231/22; C07D261/08; C07D277/28; C07D295/18; C07D305/06; C07D307/79; C07D335/02; C07D401/12; C07D417/12; C07F7/18; C07F9/40

Domestic Patent References:

WO2003099793A1	2003-12-04
WO2003099793A1	2003-12-04

Foreign References:

JPH06239817A	1994-08-30
US20020002203A1	2002-01-03

Other References: