Title:
ANTI-TUMOR METALLOCOMPLEXES OF CRUDE EXTRACT FROM CANAVALIA ENSIFORMIS
Document Type and Number:
WIPO Patent Application WO2004047733
Kind Code:
A3
Abstract:
Described are anti-tumor compositions comprising metallocomplexes of crude extract of protein from Canivallia ensiformis with calcium and magnesium. The compositions are not toxic and inhibit tumor growth.
Inventors:
LU SOU-YI
Application Number:
PCT/US2003/037144
Publication Date:
September 23, 2004
Filing Date:
November 21, 2003
Export Citation:
Assignee:
LU JIM (US)
LU SOU-YI
LU SOU-YI
International Classes:
A61K38/16; (IPC1-7): A61K9/50; A01N65/00; A61K35/78; C07K16/00
Other References:
OBATA,F. ET AL: "Concanavalin A binding various numbers of calcium and manganese ions", JOURNAL OF BIOCHEMISTRY, vol. 85, no. 4, 1979, pages 1037 - 1045, XP002978499
OBATA,F. ET AL: "Preparation of concanavalin A consisting solely of intact subunits", JOURNAL OF BIOCHEMISTRY, vol. 84, no. 1, 1978, pages 103 - 109, XP002978500
NAKAJIMA,N. ET AL: "Plant growth inhibitory activity of L-canavanine and its mode of action", JOURNAL OF CHEMICAL ECOLOGY, vol. 27, no. 1, January 2001 (2001-01-01), pages 19 - 31, XP002978466
SWAFFAR,D.S. ET AL: "Combination therapy with 5-fluorouracil and L-canavanine: In vitro and in vivo studies", ANTI-CANCER DRUGS, vol. 6, no. 4, August 1995 (1995-08-01), pages 586 - 593, XP002978452
OBATA,F. ET AL: "Preparation of concanavalin A consisting solely of intact subunits", JOURNAL OF BIOCHEMISTRY, vol. 84, no. 1, 1978, pages 103 - 109, XP002978500
NAKAJIMA,N. ET AL: "Plant growth inhibitory activity of L-canavanine and its mode of action", JOURNAL OF CHEMICAL ECOLOGY, vol. 27, no. 1, January 2001 (2001-01-01), pages 19 - 31, XP002978466
SWAFFAR,D.S. ET AL: "Combination therapy with 5-fluorouracil and L-canavanine: In vitro and in vivo studies", ANTI-CANCER DRUGS, vol. 6, no. 4, August 1995 (1995-08-01), pages 586 - 593, XP002978452
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