FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS

Title:

FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS

Document Type and Number:

WIPO Patent Application WO/2023/244619

Kind Code:

A3

Abstract:

This document relates to flavonoid compounds and methods and materials for using flavonoid compounds to treat one or more fibrotic conditions (e.g., idiopathic pulmonary fibrosis (IPF), non-alcoholic steatohepatitis (NASH), primary sclerosing cholangitis (PSC), and/or ocular fibrosis). For example, one or more flavonoid compounds having the structure of Formula (I) or Formula (II) can be administered to a mammal (e.g., a human) having one or more fibrotic conditions (e.g., IPF, NASH, PSC, and ocular fibrosis) to treat the mammal.

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Inventors:

HAAK ANDREW (US)
O'HARA STEVEN (US)
GUICCIARDI MARIA (US)
HIRSOVA PETRA (US)
LEBRASSEUR NATHAN (US)
SCHAFER MARISSA (US)

Application Number:

PCT/US2023/025221

Publication Date:

January 18, 2024

Filing Date:

June 13, 2023

Export Citation:

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Assignee:

MAYO FOUND MEDICAL EDUCATION & RES (US)

International Classes:

A61K31/352; A61P1/16; A61P27/02; A61K45/06

Foreign References:

US20100226931A1	2010-09-09
US20200316066A1	2020-10-08
US20190336492A1	2019-11-07

Attorney, Agent or Firm:

WILLIS, Margaret, S. et al. (US)

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