Title:
INFLUENZA A VIRUS HAEMAGGLUTININ SUBTYPE H16 PROTEINS AND THEIR ENCODING NUCLEI C ACID
Document Type and Number:
WIPO Patent Application WO2002024734
Kind Code:
A3
Abstract:
A sixteenth haemagglutinin subtype of influenza A virus (H16) has been isolated from gulls in Sweden and the Netherlands. The invention provides the new virus, its haemagglutinin protein and nucleic acid encoding the same. These are particularly useful for vaccination. Of the fifteen known subtypes H1 to H15, this subtype is most closely related to H13.
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Inventors:
FOUCHIER RON (NL)
OLSEN BJORN (NL)
OSTERHAUS ALBERT (NL)
OLSEN BJORN (NL)
OSTERHAUS ALBERT (NL)
Application Number:
PCT/IB2001/001914
Publication Date:
August 15, 2002
Filing Date:
September 19, 2001
Export Citation:
Assignee:
CHIRON SPA (IT)
FOUCHIER RON (NL)
OLSEN BJORN (NL)
OSTERHAUS ALBERT (NL)
FOUCHIER RON (NL)
OLSEN BJORN (NL)
OSTERHAUS ALBERT (NL)
International Classes:
C07K14/11; C12N7/00; A61K39/00; (IPC1-7): C07K14/005; A61K39/12; C07K16/08; C07K14/11
Domestic Patent References:
| WO1993015763A1 | 1993-08-19 | |||
| WO1994006468A1 | 1994-03-31 |
Foreign References:
| US5762939A | 1998-06-09 |
Other References:
DATABASE SWISS-PROT 1 January 1990 (1990-01-01), CHAMBERS TM ET AL.: "Hemaggulitin precursor (HA1 and HA2), Access. Nb P13101", XP002195960
DATABASE SWISS-PROT 1 January 1990 (1990-01-01), NOBUSAWA E ET AL.; CHAMBERS TM ET AL.: "HA precursor, access. Nb P13103", XP002195961
DATABASE SWISS-PROT 1 January 1990 (1990-01-01), CHAMBERS TM ET AL.: "HA precursor", XP002195962
DATABASE EMBL 25 April 1990 (1990-04-25), CHAMBERS TM ET AL.: "Influenza A pilot whale HA cDNA", XP002196071
DATABASE EMBL 25 April 1990 (1990-04-25), CHAMBERS TM ET AL.: "Influenza A black-headed gull hemagglutinin", XP002196072
DATABASE EMBL 25 April 1990 (1990-04-25), CHAMBERS TM ET AL.: "Influenza A ring-billed gull HA", XP002196073
DATABASE EMBL 13 March 1992 (1992-03-13), NOBUSAWA E. ET AL.: "Influenza A gull HA gene", XP002196074
CHAMBERS ET AL: "Antigenic and molecular characterization of subtype H13 hemagglutinin of influenza virus", VIROLOGY, RAVEN PRESS, NEW YORK, NY, US, vol. 172, no. 1, September 1989 (1989-09-01), pages 180 - 188, XP002105957, ISSN: 0042-6822
NOBUSAWA E ET AL: "COMPARISON OF COMPLETE AMINO ACID SEQUENCES AND RECEPTOR-BINDING PROPERTIES AMONG 13 SEROTYPES OF HEMAGGLUTININS OF INFLUENZA A VIRUSES", VIROLOGY, vol. 182, no. 2, 1991, pages 475 - 485, XP001063166, ISSN: 0042-6822
AIR G M: "SEQUENCE RELATIONSHIPS AMONG THE HEM AGGLUTININ GENES OF 12 SUBTYPES OF INFLUENZA A VIRUS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 78, no. 12, 1981, 1981 (RECD. 1982), pages 7639 - 7643, XP001069135, ISSN: 0027-8424
GUO Y J ET AL: "Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia.", VIROLOGY, vol. 267, no. 2, 15 February 2000 (2000-02-15), pages 279 - 288, XP001063163, ISSN: 0042-6822
MATROSOVICH MIKHAIL ET AL: "The surface glycoproteins of H5 influenza viruses isolated from humans, chickens, and wild aquatic birds have distinguishable properties.", JOURNAL OF VIROLOGY, vol. 73, no. 2, February 1999 (1999-02-01), pages 1146 - 1155, XP002195827, ISSN: 0022-538X
HINSHAW V S ET AL: "ANTIGENIC AND GENETIC CHARACTERIZATION OF A NOVEL HEM AGGLUTININ SUBTYPE OF INFLUENZA A VIRUSES FROM GULLS", JOURNAL OF VIROLOGY, vol. 42, no. 3, 1982, pages 865 - 872, XP001068623, ISSN: 0022-538X
DATABASE SWISS-PROT 1 January 1990 (1990-01-01), NOBUSAWA E ET AL.; CHAMBERS TM ET AL.: "HA precursor, access. Nb P13103", XP002195961
DATABASE SWISS-PROT 1 January 1990 (1990-01-01), CHAMBERS TM ET AL.: "HA precursor", XP002195962
DATABASE EMBL 25 April 1990 (1990-04-25), CHAMBERS TM ET AL.: "Influenza A pilot whale HA cDNA", XP002196071
DATABASE EMBL 25 April 1990 (1990-04-25), CHAMBERS TM ET AL.: "Influenza A black-headed gull hemagglutinin", XP002196072
DATABASE EMBL 25 April 1990 (1990-04-25), CHAMBERS TM ET AL.: "Influenza A ring-billed gull HA", XP002196073
DATABASE EMBL 13 March 1992 (1992-03-13), NOBUSAWA E. ET AL.: "Influenza A gull HA gene", XP002196074
CHAMBERS ET AL: "Antigenic and molecular characterization of subtype H13 hemagglutinin of influenza virus", VIROLOGY, RAVEN PRESS, NEW YORK, NY, US, vol. 172, no. 1, September 1989 (1989-09-01), pages 180 - 188, XP002105957, ISSN: 0042-6822
NOBUSAWA E ET AL: "COMPARISON OF COMPLETE AMINO ACID SEQUENCES AND RECEPTOR-BINDING PROPERTIES AMONG 13 SEROTYPES OF HEMAGGLUTININS OF INFLUENZA A VIRUSES", VIROLOGY, vol. 182, no. 2, 1991, pages 475 - 485, XP001063166, ISSN: 0042-6822
AIR G M: "SEQUENCE RELATIONSHIPS AMONG THE HEM AGGLUTININ GENES OF 12 SUBTYPES OF INFLUENZA A VIRUS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 78, no. 12, 1981, 1981 (RECD. 1982), pages 7639 - 7643, XP001069135, ISSN: 0027-8424
GUO Y J ET AL: "Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia.", VIROLOGY, vol. 267, no. 2, 15 February 2000 (2000-02-15), pages 279 - 288, XP001063163, ISSN: 0042-6822
MATROSOVICH MIKHAIL ET AL: "The surface glycoproteins of H5 influenza viruses isolated from humans, chickens, and wild aquatic birds have distinguishable properties.", JOURNAL OF VIROLOGY, vol. 73, no. 2, February 1999 (1999-02-01), pages 1146 - 1155, XP002195827, ISSN: 0022-538X
HINSHAW V S ET AL: "ANTIGENIC AND GENETIC CHARACTERIZATION OF A NOVEL HEM AGGLUTININ SUBTYPE OF INFLUENZA A VIRUSES FROM GULLS", JOURNAL OF VIROLOGY, vol. 42, no. 3, 1982, pages 865 - 872, XP001068623, ISSN: 0022-538X
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