ANTI-hK2 CHIMERIC ANTIGEN RECEPTOR (CAR)

Title:

ANTI-hK2 CHIMERIC ANTIGEN RECEPTOR (CAR)

Document Type and Number:

Japanese Patent JP2023153779

Kind Code:

A

Abstract:

To provide a chimeric antigen receptor (CAR) that specifically binds to human Kallikrein-2 (hK2), and immunoresponsive cells comprising such CARs, for treatment of cancer.SOLUTION: A chimeric antigen receptor (CAR) comprises (a) an extracellular domain that specifically binds to a human Kallikrein-2 (hK2) antigen, (b) a transmembrane domain, and (c) an intracellular signaling domain optionally comprising at least one co-stimulatory domain.SELECTED DRAWING: None

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Inventors:

RAYMOND BRITTINGHAM
RAJKUMAR GANESAN
SHERRY LA PORTE
LEE JEONG
LUO JINQUAN
THERESA MCDEVITT
SHEN FEI
SINGH SANJAYA
SONG DEGANG
SATHYADEVI VENKATARAMANI
LEE JOHN
ZHAO YONGHONG

Application Number:

JP2023112000A

Publication Date:

October 18, 2023

Filing Date:

July 07, 2023

Export Citation:

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Assignee:

JANSSEN BIOTECH INC

International Classes:

C12N15/13; A61K35/17; A61K39/395; A61P35/00; C07K16/28; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/62; C12N15/63; C12Q1/04; G01N33/574

Attorney, Agent or Firm:

Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Koichi Iwata

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