Title:
【発明の名称】アンチセンスオリゴヌクレオチドの結合の同定
Document Type and Number:
Japanese Patent JP2001501479
Kind Code:
A
Abstract:
A method for identifying an antisense oligonucleotide capable of binding to a target mRNA, which comprises contacting the target mRNA with each member of an oligonucleotide library separately under hybridization conditions, removing unhybridized material and determining which member or members hybridize; wherein the oligonucleotide library comprises a plurality of distinct nucleotide sequences of a predetermined common length, and wherein each nucleotide sequence comprises a known sequence of 4 to 8 bases and all possible combinations of the known sequence are present in the library.
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Inventors:
Schmidt, Guntel
Thomson, Andrew, Fujin
Thomson, Andrew, Fujin
Application Number:
JP51729198A
Publication Date:
February 06, 2001
Filing Date:
October 06, 1997
Export Citation:
Assignee:
Blacks Group Limited
International Classes:
G01N37/00; C12N15/09; C12N15/113; C12Q1/68; C12Q1/6811; C12Q1/6837; G01N33/53; (IPC1-7): C12N15/09; C12Q1/68
Attorney, Agent or Firm:
Atsushi Nakajima (2 outside)