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Title:
A NEW POLYPEPTIDE - HUMAN DIHYDROORATASE 17 AND THE POLYNUCLEOTIDE ENCODING IT
Document Type and Number:
WIPO Patent Application WO/2001/083724
Kind Code:
A1
Abstract:
The present invention discloses a new polypeptide - human dihydroorotase 17, the polynucleotide encoding it and a method of producing the polypeptide by DNA recombinant technology. The present invention further discloses a method treating various disorders, e.g., malignant neoplasm, hematopathy, HIV infection and immunological disease and various inflammation etc. The present invention also discloses an antagonist of the polypeptide and its therapeutic action. The present invention further discloses the use of the polynucleotide encoding the new human dihydroorotase 17.

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Inventors:
MAO YUMIN (CN)
XIE YI (CN)
Application Number:
PCT/CN2001/000633
Publication Date:
November 08, 2001
Filing Date:
April 28, 2001
Export Citation:
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Assignee:
SHANGHAI BIOWINDOW GENE DEV (CN)
MAO YUMIN (CN)
XIE YI (CN)
International Classes:
A61P35/00; A61P37/00; C12N9/86; A61K38/00; (IPC1-7): C12N9/02; A61K38/17; A61P35/00; A61P37/00; C07K14/435; C07K14/47; C12N15/12; C12N15/52; C12N15/63; C12N15/85
Other References:
DATABASE GENBANK [online] ROSWELL PARK CANCER INSTITUTE HUMAN PAC LIBRARY; 26 November 1998 (1998-11-26), MUZNY D. ET AL.: "Homo sapiens 12q13 PAC RPC13-432I18", Database accession no. AC004486
SATO S. ET AL.: "Structural analysis of arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covored by sicty P1 and TAC clones", DNA RES., vol. 7, no. 2, 2000, pages 131 - 135
IWAHANA H. ET AL., BIOCHEM. BIOPHYS. RES. COMMUN., vol. 219, no. 1, 6 February 1996 (1996-02-06), pages 249 - 255
HUGHES L.E. ET AL., CURR. MICROBIOL., vol. 39, no. 4, October 1999 (1999-10-01), pages 175 - 179
Attorney, Agent or Firm:
SHANGHAI HUA DONG PATENT AGENCY (Shanghai 1, CN)
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