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WO/2013/073480A9 |
Provided is a cationic lipid with which it is possible to achieve high intracellular expression efficiency when used as a nucleic acid delivery carrier. The lipid is a compound represented by formula (1) (where Xa and Xb are, independent...
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WO/2013/099553A1 |
Provided is a novel 2-fluorophenylpropionic acid derivative which has excellent anti-inflammatory/analgesic effects, while avoiding side effects such as gastrointestinal disorders, namely a 2-fluorophenylpropionic acid derivative represe...
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WO/2013/092350A1 |
The present invention relates to novel N-arylamidine-substituted trifluoroethyl sulfide derivatives of the formula (I) in which X1, X2, X3, X4, R1, R2, R3, n are each defined as specified in the description, to the use thereof as acarici...
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WO/2013/088972A1 |
Provided is a compound represented by general formula (1). (1) In general formula (1), R1 is either a protecting group for a hydroxyl group or a hydrogen atom. R2 is either a methyl group or an ethyl group.
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WO/2013/083568A1 |
The invention relates to selective estrogen receptor modulators (SERMs), to methods for the production thereof, to the use thereof to treat and/or prevent diseases, and to the use thereof to produce drugs for the treatment and/or prevent...
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WO/2013/083934A1 |
The present invention relates to a novel liquid methionine compound, originating from the mother liquor from the crystallisation of methionine produced by fermentation, comprising between 30 and 50% methionine by weight and having a dry ...
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WO/2013/083024A1 |
Disclosed is a benzothiazole compound as represented by formula (I), wherein X, Y, R1, R2 and Z' are as defined in the specification. Also disclosed are the preparation method, intermediate and uses of the compound. The benzothiazole com...
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WO/2013/076968A1 |
This method for producing a β-mercaptocarboxylic acid represented by general formula (3) involves: a step of obtaining a reaction solution including a compound represented by general formula (2) by reacting, under atmospheric pressure, ...
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WO/2013/071400A1 |
The present application relates to novel apocynin-lopioc acid covalent conjugates, compositions comprising these compounds and their use, in particular for the treatment of diseases, disorders or conditions that are mediated by oxidative...
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WO/2013/073363A1 |
[Problem] When a thermosetting (meth)acrylic resin that has been colored red, blue, or the like by a coloring agent is exposed to a 150°C atmosphere or a 120°C atmosphere as a high-temperature durability test, rapid discoloration takes...
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WO/2013/072436A1 |
The present invention relates to the use of a compound of formula (I) : wherein: - R represents –OH or –NH2;- A1 represents a divalent alkylene radical, straight or branched, having from 2 to 20 carbon atoms; - A2 represents a divale...
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WO/2013/070402A1 |
Disclosed herein is a neutral or overbased salt of a sulfurized alkylhydroxyaromatic compound obtained by the process comprising the steps of (a) sulfurizing an alkylhydroxyaromatic compound derived from alkylation of a hydroxyaromatic c...
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WO/2013/062024A1 |
Provided is a plant disease control agent which, regardless of where employed, effectively controls a wide range of plant pathogens. This plant disease control agent contains, as an active component, a compound represented by formula (I)...
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WO/2013/059173A1 |
A bridged dimeric or oligomeric phenolic compound comprising: at least one monomer unit (a) of phenol or an alkyl-substituted phenol wherein the alkyl group contains 1 to 8 carbon atoms, or mixtures thereof; at least one monomer unit (b)...
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WO/2013/053940A1 |
The present invention provides a method for the synthesis of 18F-labelled biomolecules, which is amenable to automation. The present invention also provides a cassette for automating the method of the invention. The method of the present...
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WO/2013/053941A1 |
The present invention provides a method for the synthesis of 18F-labelled biomolecules, which is amenable to automation. The present invention also provides a cassette for automating the method of the invention. The method of the present...
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WO/2013/050547A1 |
The subject of the present invention is a compound of formula (I) below, the addition salts thereof, the dimer thereof and also the organic or inorganic acid salts thereof, the optical isomers thereof, the geometric isomers thereof, and ...
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WO/2013/051715A1 |
Provided are: a palladium separating agent which is capable of separating palladium ions in a short time with high selectivity from solutions that contain palladium ions at low to high concentrations; and a method for separating palladiu...
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WO/2013/042800A1 |
Provided is a chromene compound which has a sulfur-containing substitute represented by formula (2) at the carbon atom in the 6-position and/or the 7-position of an indeno(2,1-f)naphtho(1,2-b)pyran structure. This chromene compound has e...
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WO/2013/033519A1 |
Provided herein are poly-capped estolides, including those of Formula (IV): in which n is an integer equal to or greater than 0; m is an integer equal to or greater than 2; R1 is selected from optionally substituted alkyl that is saturat...
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WO/2013/026739A1 |
The acid-catalysed esterification of mercaptoalkyl alcohols with carboxylic acids to give mercaptoalkyl carboxylates typically results in the formation of unwanted, usually sparingly soluble by-products. The process according to the inve...
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WO/2013/026885A1 |
The present invention relates to unsaturated vicinal dithioethers of general formula (I) wherein n is an integer from 1 to 12, wherein m is 0 or 1, wherein X is selected from formules wherein Y is selected from the group consisting of -C...
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WO/2013/027843A1 |
Provided is a glucoside compound that can be produced inexpensively and is capable of imparting a phosphoramidite with which a nucleic acid can be produced at a high yield and high purity. The glucoside compound is represented by chemica...
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WO/2012/170952A9 |
Here described are compounds of formula I: wherein R1 and R2 is independently selected from a group consisting of C10 to C18 alkyl, C12 to C18 alkenyl, and oleyl group; wherein R3 and R4 are independently selected from a group consisting...
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WO/2013/018501A1 |
This halogen-terminated sulfur-containing polymer is represented by the following formula: X-(R-Sr)n-R-X (wherein R represents an ether bond-containing alkyl group having 3-26 carbon atoms, X represents a halogen atom, n represents an in...
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WO/2013/016839A1 |
Provided are photocurable compositions prepared from mercapto-benzophenone compounds as the key raw materials. The aim of the present invention is to solve the problems in the prior photocurable art that the small molecular photoinitiato...
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WO/2013/006971A1 |
Novel sulphur containing compounds of the formula RSSCH3, wherein R is pyridine, phenylamine or pynmidine, and pharmaceutically acceptable salts thereof are disclosed, which have utility as anti-proliferative agents against mammalian cel...
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WO/2013/004190A1 |
Disclosed are immune-modulators of formula (I), the preparation method thereof, a pharmaceutical composition containing the immune-modulators, and the use of the pharmaceutical composition as a drug, especially as an immune-modulating dr...
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WO/2012/176918A1 |
Specifically provided is a chromene compound represented by formula (1), which has a short fading half-life even at low temperatures in a common polymer solid matrix. (In formula (1), R1 represents a hydroxyl group or the like; each of R...
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WO/2012/171484A1 |
Disclosed is a substituted cyanoaniline compound or a salt thereof, wherein the compound has a structure represented by General Formula I. The compound of General Formula I has broad-spectrum fungicidal activity in the field of agricultu...
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WO/2012/173666A1 |
Provided herein are compounds of the formula (I): in which n is an integer equal to or greater than 1; m is an integer equal to or greater than 1; R2 is selected from hydrogen and optionally substituted alkyl that is saturated or unsatur...
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WO/2012/167869A1 |
The present invention provides new amino lipids and a convenient method for synthesising these compounds. These (cationic) amino lipids have good properties as transfection agents. The method is an economic versatile two step synthesis a...
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WO/2012/165648A1 |
The present invention provides a compound having an excellent efficacy for controlling weeds. A cyclohexanone compound of the formula (I): wherein m is an integer of 1, 2 or 3; n is an integer of any one of 1 to 5; X represents CH2, O, S...
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WO/2012/159213A1 |
There are provided compounds comprising optionally substituted (FORMULA I) fused with one or two optionally substituted (FORMULA II), wherein A and E each independently represent -CH 2 -, -NH-, -O-, -S-, or -C(=O)- and B represents a bon...
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WO/2012/157808A1 |
The present invention relates to a heat resistant additive for a novel polymer resin and a polymer resin composition comprising same, and more specifically, to a heat resistant additive for a polymer resin containing a thio-compound havi...
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WO/2012/154904A1 |
Disclosed are compounds that inhibit RNase H activity of retroviruses, for example, a compound of formula (I) wherein R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts, solvates, stereoisomers, and prod...
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WO/2012/150747A1 |
The present invention relates to a method for manufacturing ajoene enhanced fat and oil using milk fat and a method for manufacturing butter containing ajoene comprising the steps of: preparing any one or more allicin containing garlic i...
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WO/2012/143412A1 |
The invention relates to a method for producing a purified solution containing L-cysteine from a fermentation broth containing L-cysteine. In said method, the fermentation broth containing L-cysteine, at a pH value from pH 6 to 9, is bro...
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WO/2012/139227A1 |
The present invention provides a method of preventing or treating cardiovascular dysfunction by administering a therapeutically effective amount of (a) one or more of (i) S-adenosylmethionine or a derivative or pharmaceutically acceptabl...
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WO/2012/130299A1 |
Novel compounds of the formula (I) wherein R1, R2, D, A, B and X have the meanings defined herein, pharmaceutical compositions comprising them as active ingredient, as well as their use in medicine, in particular as peptidase inhibitors,...
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WO/2012/132558A1 |
An oxime ester compound represented by general formula (1) [wherein R1 to R4 are each OR11, COOR11, or the like; R11 is a hydrogen atom, a C1-20 alkyl group, a C6-30 aryl group, a C7-30 arylalkyl group, or a C2-20 heterocyclic group, the...
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WO/2012/134337A1 |
The invention relates to the chemical and pharmaceutical branches of industry and concerns the chemical functionalization of fullerene C60,and specifically the development of a method for producing a new class of sulfur-containing fuller...
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WO/2012/129473A1 |
The present invention provides complexes of gallium with a ligand, methods of making the complexes, methods of using the complexes and pharmaceutical gallium compositions comprising the complexes, in particular those compositions suitabl...
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WO/2012/127996A1 |
The present invention provides a method for producing a 1,2-benzisothiazol-3-one compound whereby the alkyl halide by-product that is generated when a 2-(alkylthio)benzonitrile compound and a halogenation agent are reacted in the presenc...
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WO/2012/119507A1 |
Disclosed is a method for preparing 3-mercaptopropionate which comprises the addition of Na2SO3 in course of the reaction of H2S and S2R2, wherein R = -CH2CH2COOR1, and R1 is selected from C1-8 alkyl, aryl, C1-8 alkyl or C1-8 Naphthenic ...
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WO/2012/115236A1 |
Provided are a novel heterocyclic compound represented by formula (1), and a field-effect transistor having a semiconductor layer comprising the aforementioned compound. Also provided is a method for producing an intermediate enabling th...
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WO/2012/113829A1 |
The present invention relates to a heat-curable composition comprising (a) at least one compound which is capable of undergoing cationic polymerization; and (b) at least one sulfonium sulfate selected from compounds of the formulae Ia an...
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WO/2012/113665A1 |
The invention relates to a compound containing 86 to 97 wt % of 2-hydroxy-4-methylthio butyric acid nitrile, 2 to 14 wt % of water, 0.05 to 0.5 wt % of HCN and having a pH value from 1 to 4, measured with a pH electrode at 23°C. The inv...
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WO/2012/115151A1 |
Provided is an aggregate of hollow particles that is aggregated from a plurality of particles capable of self-organization, and that is characterized in that a metal core is modified by a metal core surface modifier that is provided with...
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WO/2012/113664A1 |
The invention relates to a method for producing 2-hydroxy-4-(methylthio)butanenitrile, wherein 3-methylmercapto-propionaldehyde is reacted with hydrogen cyanide in the presence of a base as catalyst into nitrile in a main reaction zone, ...
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